Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.39 |
| ▸ | RAB9A | P51151 | 2/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.39 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.39 |
| ▸ | RELA | Q04206 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.37 |
| ▸ | PKM | P14618 | 2/20 | 0.37 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.36 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.36 |
| ▸ | CA12 | O43570 | 1/20 | 0.35 |
| ▸ | CA1 | P00915 | 1/20 | 0.35 |
| ▸ | CA2 | P00918 | 1/20 | 0.35 |
| ▸ | CA9 | Q16790 | 1/20 | 0.35 |
| ▸ | RCE1 | Q9Y256 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15900342 | 1.00 | NPSR1 (0.54) | NPSR1SMN1; SMN2L3MBTL1RAB9ANPC1 | |
| SCHEMBL2408051 | 0.90 | NPSR1 (0.52) | NPSR1SMN1; SMN2L3MBTL1RAB9ANPC1 | |
| SCHEMBL31214346 | 0.90 | NPSR1 (0.52) | NPSR1SMN1; SMN2L3MBTL1RAB9ANPC1 | |
| SCHEMBL9091123 | 0.87 | NPSR1 (0.71) | NPSR1SMN1; SMN2L3MBTL1RAB9ANPC1 | |
| SCHEMBL12108293 | 0.86 | NPSR1 (0.52) | NPSR1SMN1; SMN2L3MBTL1RAB9ANPC1 | |
| SCHEMBL23900531 | 0.85 | NPSR1 (0.47) | NPSR1SMN1; SMN2L3MBTL1RAB9ANPC1 | |
| SCHEMBL15900363 | 0.85 | NPSR1 (0.47) | NPSR1SMN1; SMN2L3MBTL1RAB9ANPC1 | |
| SCHEMBL11730515 | 0.83 | NPSR1 (0.54) | NPSR1SMN1; SMN2L3MBTL1RAB9ANPC1 | |
| SCHEMBL2183292 | 0.83 | NPSR1 (0.58) | NPSR1SMN1; SMN2L3MBTL1RAB9ANPC1 | |
| SCHEMBL2408256 | 0.80 | NPSR1 (0.61) | NPSR1SMN1; SMN2RAB9AALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115485273-B | N- (heterocyclyl and heterocyclylalkyl) -3-benzyl pyridin-2-amine derivatives as SSTR4 agonists | 武田药品工业株式会社 | 2024-08-13 | — | — | CN | disclosed |
| CN-115485273-A | N- (heterocyclyl and heterocyclylalkyl) -3-benzylpyridin-2-amine derivatives as SSTR4 agonists | 武田药品工业株式会社 | 2022-12-16 | — | — | CN | disclosed |