Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IKBKE | Q14164 | 1/20 | 0.48 |
| ▸ | TBK1 | Q9UHD2 | 1/20 | 0.48 |
| ▸ | HTR1D | P28221 | 1/20 | 0.39 |
| ▸ | FABP7 | O15540 | 3/20 | 0.39 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.38 |
| ▸ | GSK3B | P49841 | 1/20 | 0.37 |
| ▸ | FABP5 | Q01469 | 2/20 | 0.37 |
| ▸ | FABP3 | P05413 | 1/20 | 0.37 |
| ▸ | MAPK14 | Q16539 | 4/20 | 0.35 |
| ▸ | BRD4 | O60885 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | USP2 | O75604 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.34 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.34 |
| ▸ | ATM | Q13315 | 1/20 | 0.33 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30023414 | 0.86 | IKBKE (0.41) | IKBKETBK1HTR1DFABP7KDM4C | |
| SCHEMBL31229851 | 0.76 | IKBKE (0.48) | IKBKETBK1HTR1DFABP7KDM4C | |
| SCHEMBL30023029 | 0.74 | IKBKE (0.50) | IKBKETBK1HTR1DFABP7KDM4C | |
| SCHEMBL5975156 | 0.72 | KDM4C (0.40) | IKBKETBK1HTR1DKDM4CMAPK14 | |
| SCHEMBL30570851 | 0.71 | MAPK14 (0.39) | IKBKETBK1HTR1DFABP7FABP5 | |
| SCHEMBL420951 | 0.70 | IKBKE (0.44) | IKBKETBK1FABP7FABP5FABP3 | |
| SCHEMBL1572799 | 0.70 | GSK3B (0.59) | IKBKETBK1FABP7GSK3B | |
| SCHEMBL28901595 | 0.68 | IKBKE (0.44) | IKBKETBK1HTR1DFABP7FABP5 | |
| SCHEMBL23930140 | 0.68 | IKBKE (0.43) | IKBKETBK1HTR1DFABP7GSK3B | |
| SCHEMBL30023884 | 0.68 | IKBKE (0.43) | IKBKETBK1HTR1DFABP7GSK3B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115397822-A | CBP/EP300 inhibitors and uses thereof | 南京药石科技股份有限公司 | 2022-11-25 | — | — | CN | disclosed |