Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATF4 | P18848 | 20/20 | 0.62 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19569477 | 1.00 | ATF4 (0.62) | ATF4 | |
| SCHEMBL22397232 | 1.00 | ATF4 (0.62) | ATF4 | |
| SCHEMBL22397259 | 0.96 | ATF4 (0.60) | ATF4 | |
| SCHEMBL20974031 | 0.94 | ATF4 (0.60) | ATF4 | |
| SCHEMBL22612400 | 0.88 | ATF4 (0.57) | ATF4 | |
| SCHEMBL19569507 | 0.86 | ATF4 (0.79) | ATF4 | |
| SCHEMBL30024698 | 0.86 | ATF4 (0.79) | ATF4 | |
| SCHEMBL20974268 | 0.85 | ATF4 (0.60) | ATF4 | |
| SCHEMBL22612425 | 0.85 | ATF4 (0.58) | ATF4 | |
| SCHEMBL20999243 | 0.85 | ATF4 (0.51) | ATF4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4356971-A2 | MODULATORS OF THE INTEGRATED STRESS PATHWAY | Calico Life Sciences LLC (US) | 2024-04-24 | — | — | EP | disclosed |
| CN-115947681-A | Modulators of integrated stress pathways | 卡里科生命科学有限责任公司 | 2023-04-11 | — | — | CN | disclosed |
| CN-109641844-B | Modulators of integrated stress pathways | 卡里科生命科学有限责任公司 | 2022-11-01 | — | — | CN | disclosed |