Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2C | P28335 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | ENPP1 | P22413 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | NUDT1 | P36639 | 1/20 | 0.32 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.31 |
| ▸ | PDE1A | P54750 | 3/20 | 0.30 |
| ▸ | PDE1B | Q01064 | 3/20 | 0.30 |
| ▸ | PDE1C | Q14123 | 3/20 | 0.30 |
| ▸ | TNKS | O95271 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24529236 | 0.83 | HTR2C (0.47) | HTR2CL3MBTL1ENPP1NUDT1HCRTR2 | |
| SCHEMBL24387327 | 0.82 | HTR2C (0.41) | HTR2CL3MBTL1 | |
| SCHEMBL24386943 | 0.79 | HTR2C (0.41) | HTR2CL3MBTL1 | |
| SCHEMBL5486787 | 0.78 | EPHB4 (0.45) | HTR2CL3MBTL1 | |
| SCHEMBL23571797 | 0.77 | HPGD (0.33) | L3MBTL1HPGDSMN1; SMN2MEN1KMT2A | |
| SCHEMBL24529479 | 0.77 | HTR2C (0.47) | HTR2CL3MBTL1NUDT1TNKS | |
| SCHEMBL31250025 | 0.76 | ENPP1 (0.44) | L3MBTL1HPGDENPP1HCRTR2 | |
| SCHEMBL23572068 | 0.75 | PDE1A (0.33) | HPGDSMN1; SMN2MEN1KMT2APDE1A | |
| SCHEMBL19865160 | 0.74 | L3MBTL1 (0.53) | HTR2CL3MBTL1NUDT1TNKS | |
| SCHEMBL103894 | 0.73 | HTR2C (0.53) | HTR2CL3MBTL1NUDT1TNKS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4076459-A1 | PRMT5 INHIBITORS | Merck Sharp & Dohme LLC (US) | 2022-10-26 | — | — | EP | disclosed |