SCHEMBL30025642

SCHEMBL30025642

O=C(COc1ccc(Cl)c(F)c1)NC12CCC(NC(=O)COc3ccc(Cl)cc3)(CC1)[C@@H](O)C2

nearest known ligand 0.58

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
▸ ATF4 P18848 20/20 0.58

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19569364 1.00 ATF4 (0.58) ATF4
SCHEMBL22669150 1.00 ATF4 (0.58) ATF4
SCHEMBL19555453 1.00 ATF4 (0.58) ATF4
SCHEMBL31525210 0.96 ATF4 (0.59) ATF4
SCHEMBL30961497 0.96 ATF4 (0.59) ATF4
SCHEMBL30961482 0.96 ATF4 (0.59) ATF4
SCHEMBL19569747 0.96 ATF4 (0.59) ATF4
SCHEMBL19569455 0.96 ATF4 (0.59) ATF4
SCHEMBL19569452 0.96 ATF4 (0.59) ATF4
SCHEMBL19569648 0.95 ATF4 (0.56) ATF4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115947681-A Modulators of integrated stress pathways 卡里科生命科学有限责任公司 2023-04-11 — — CN disclosed
CN-109641844-B Modulators of integrated stress pathways 卡里科生命科学有限责任公司 2022-11-01 — — CN disclosed
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