Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATF4 | P18848 | 19/20 | 0.62 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20973797 | 1.00 | ATF4 (0.62) | ATF4SMN1; SMN2 | |
| SCHEMBL20974024 | 0.91 | ATF4 (0.53) | ATF4SMN1; SMN2 | |
| SCHEMBL30025024 | 0.91 | ATF4 (0.53) | ATF4SMN1; SMN2 | |
| SCHEMBL19569493 | 0.88 | ATF4 (0.64) | ATF4 | |
| SCHEMBL30025154 | 0.88 | ATF4 (0.64) | ATF4 | |
| SCHEMBL19555840 | 0.87 | ATF4 (0.63) | ATF4 | |
| SCHEMBL19569507 | 0.86 | ATF4 (0.79) | ATF4 | |
| SCHEMBL30024698 | 0.86 | ATF4 (0.79) | ATF4 | |
| SCHEMBL21117001 | 0.86 | ATF4 (0.55) | ATF4SMN1; SMN2 | |
| SCHEMBL19569587 | 0.85 | ATF4 (0.66) | ATF4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115947681-A | Modulators of integrated stress pathways | 卡里科生命科学有限责任公司 | 2023-04-11 | — | — | CN | disclosed |
| CN-109641844-B | Modulators of integrated stress pathways | 卡里科生命科学有限责任公司 | 2022-11-01 | — | — | CN | disclosed |