Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.68 |
| ▸ | ATM | Q13315 | 1/20 | 0.68 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.64 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.64 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.64 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.64 |
| ▸ | BLM | P54132 | 1/20 | 0.64 |
| ▸ | MEN1 | O00255 | 1/20 | 0.61 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.61 |
| ▸ | MTNR1A | P48039 | 2/20 | 0.60 |
| ▸ | MTNR1B | P49286 | 2/20 | 0.60 |
| ▸ | APP | P05067 | 1/20 | 0.60 |
| ▸ | ABCB1 | P08183 | 2/20 | 0.58 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.58 |
| ▸ | BCHE | P06276 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL67744 | 1.00 | KDM4E (0.68) | KDM4EATMCYP1A2CYP3A4CYP2D6 | |
| Hydrochloric Acid SCHEMBL1298567 | 0.98 | KDM4E (0.66) | KDM4EATMCYP1A2CYP3A4CYP2D6 | |
| SCHEMBL2742565 | 0.94 | KDM4E (0.68) | KDM4EATMCYP1A2CYP3A4CYP2D6 | |
| Hydrochloric Acid SCHEMBL17821823 | 0.93 | KDM4E (0.66) | KDM4EATMCYP1A2CYP3A4CYP2D6 | |
| SCHEMBL5209173 | 0.91 | MTNR1A (0.64) | KDM4EATMCYP1A2CYP3A4CYP2D6 | |
| SCHEMBL3272392 | 0.91 | SLC2A1 (0.54) | KDM4EATMCYP1A2CYP3A4CYP2D6 | |
| SCHEMBL31040310 | 0.90 | KDM4E (0.54) | KDM4EATMCYP1A2CYP3A4CYP2D6 | |
| Hydrochloric Acid SCHEMBL5628566 | 0.89 | SLC2A1 (0.52) | KDM4EATMCYP1A2CYP3A4CYP2D6 | |
| SCHEMBL3712764 | 0.88 | MEN1 (0.60) | KDM4ECYP1A2CYP3A4CYP2D6CYP2C9 | |
| SCHEMBL23206799 | 0.88 | KDM4E (0.59) | KDM4EATMCYP1A2CYP3A4CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250340555-A1 | Tricyclic Fused Heterocyclic PDE3/4 Dual Inhibitor and Use Thereof | XIZANG HAISCO PHARMACEUTICAL CO LTD (CN) | 2025-11-06 | — | — | US | disclosed |
| EP-4606427-A2 | TRICYCLIC FUSED HETEROCYCLIC PDE3/4 DUAL INHIBITOR AND USE THEREOF | Xizang Haisco Pharmaceutical Co., Ltd. (CN) | 2025-08-27 | — | — | EP | disclosed |
| US-20250059186-A1 | Tricyclic Fused Heterocyclic PDE3/4 Dual Inhibitor and Use Thereof | XIZANG HAISCO PHARMACEUTICAL CO., LTD. (CN) | 2025-02-20 | — | — | US | disclosed |
| EP-4450500-A1 | TRICYCLIC FUSED HETEROCYCLIC PDE3/4 DUAL INHIBITOR AND USE THEREOF | Xizang Haisco Pharmaceutical Co., Ltd. (CN) | 2024-10-23 | — | — | EP | disclosed |
| CN-115260185-B | Deuterated derivative of corydaline and stephanine and preparation method thereof | 杨征 | 2024-09-24 | — | — | CN | disclosed |
| CN-115260185-A | Deuterated derivatives of corydaline and stepholidine and preparation method thereof | 杨征 | 2022-11-01 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250340555-A1 | Tricyclic Fused Heterocyclic PDE3/4 Dual Inhibitor and Use Thereof | PDE3A, PDE3B, PDE4A | KDM4E 1093/4885ATM 3231/4885CYP1A2 997/4885 |
| US-20250059186-A1 | Tricyclic Fused Heterocyclic PDE3/4 Dual Inhibitor and Use Thereof | PDE3A, PDE3B, PDE4A | KDM4E 1093/4885ATM 3231/4885CYP1A2 997/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.