Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.47 |
| ▸ | P4HTM | Q9NXG6 | 5/20 | 0.47 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | ASPH | Q12797 | 2/20 | 0.44 |
| ▸ | KDM8 | Q8N371 | 2/20 | 0.44 |
| ▸ | KMO | O15229 | 3/20 | 0.42 |
| ▸ | ECE1 | P42892 | 2/20 | 0.41 |
| ▸ | P4HA1 | P13674 | 1/20 | 0.41 |
| ▸ | MIF | P14174 | 1/20 | 0.41 |
| ▸ | SIRT6 | Q8N6T7 | 1/20 | 0.41 |
| ▸ | CA12 | O43570 | 1/20 | 0.40 |
| ▸ | CA1 | P00915 | 1/20 | 0.40 |
| ▸ | CA2 | P00918 | 1/20 | 0.40 |
| ▸ | CA3 | P07451 | 1/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | CA4 | P22748 | 1/20 | 0.40 |
| ▸ | CA6 | P23280 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1425220 | 1.00 | GPR35 (0.50) | GPR35KDM4EL3MBTL1P4HTMALOX15 | |
| SCHEMBL1425031 | 0.98 | GPR35 (0.49) | GPR35KDM4EL3MBTL1P4HTMALOX15 | |
| Hydrochloric Acid SCHEMBL26638664 | 0.98 | GPR35 (0.49) | GPR35KDM4EL3MBTL1P4HTMALOX15 | |
| Potassium SCHEMBL1425033 | 0.98 | GPR35 (0.49) | GPR35KDM4EL3MBTL1P4HTMALOX15 | |
| SCHEMBL29368707 | 0.85 | GPR35 (0.49) | GPR35KDM4EL3MBTL1P4HTMALOX15 | |
| SCHEMBL18009392 | 0.85 | GPR35 (0.49) | GPR35KDM4EL3MBTL1P4HTMALOX15 | |
| SCHEMBL23714349 | 0.84 | MAPK1 (0.47) | KDM4EL3MBTL1P4HTMMAPK1PKM | |
| SCHEMBL30111868 | 0.84 | MAPK1 (0.47) | KDM4EL3MBTL1P4HTMMAPK1PKM | |
| Potassium Ion SCHEMBL1425032 | 0.82 | GRM4 (0.38) | GPR35KDM4EL3MBTL1P4HTMALOX15 | |
| SCHEMBL21045825 | 0.81 | HTT (0.49) | GPR35KDM4EL3MBTL1P4HTMALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4271674-A1 | CARBOXY-BENZIMIDAZOLE GLP-1R MODULATING COMPOUNDS | GILEAD SCIENCES, INC. (US) | 2023-11-08 | — | — | EP | disclosed |
| EP-4271672-A1 | CARBOXY-BENZIMIDAZOLE GLP-1R MODULATING COMPOUNDS | GILEAD SCIENCES, INC. (US) | 2023-11-08 | — | — | EP | disclosed |
| WO-2022225914-A1 | CARBOXY-BENZIMIDAZOLE GLP-1R MODULATING COMPOUNDS | GILEAD SCIENCES, INC. (US) | 2022-10-27 | — | — | WO | disclosed |
| WO-2022225941-A1 | CARBOXY-BENZIMIDAZOLE GLP-1R MODULATING COMPOUNDS | GILEAD SCIENCES, INC. (US) | 2022-10-27 | — | — | WO | disclosed |