Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | TACR1 | P25103 | 1/20 | 0.34 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.32 |
| ▸ | AADAT | Q8N5Z0 | 2/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.31 |
| ▸ | BTK | Q06187 | 1/20 | 0.31 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.31 |
| ▸ | GHSR | Q92847 | 2/20 | 0.31 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.30 |
| ▸ | P2RX7 | Q99572 | 2/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30031487 | 0.95 | AADAT (0.33) | MAPTTACR1AADATTP53RXFP1 | |
| SCHEMBL30032122 | 0.95 | AADAT (0.33) | MAPTTACR1AADATTP53RXFP1 | |
| SCHEMBL30032226 | 0.95 | AADAT (0.33) | MAPTTACR1AADATTP53RXFP1 | |
| SCHEMBL30031916 | 0.95 | AADAT (0.33) | MAPTTACR1AADATTP53RXFP1 | |
| SCHEMBL30031257 | 0.94 | TACR1 (0.34) | MAPTTACR1NR3C2AADATMDM2 | |
| SCHEMBL30031253 | 0.93 | AADAT (0.33) | MAPTTACR1AADATTP53RXFP1 | |
| SCHEMBL30031425 | 0.89 | AADAT (0.34) | MAPTTACR1AADATTP53 | |
| SCHEMBL30031821 | 0.89 | AADAT (0.34) | MAPTTACR1AADATTP53 | |
| SCHEMBL30031819 | 0.89 | AADAT (0.34) | MAPTTACR1AADATTP53 | |
| SCHEMBL30031479 | 0.89 | AADAT (0.35) | MAPTAADATTP53RXFP1BTK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022214937-A1 | SUBSTITUTED TETRACYCLIC CARBOXYLIC ACIDS, ANALOGUES THEREOF, AND METHODS USING SAME | ARBUTUS BIOPHARMA CORPORATION (CA) | 2022-10-13 | — | — | WO | disclosed |