Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1C3 | P42330 | 2/20 | 0.52 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.52 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.52 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.49 |
| ▸ | MAPT | P10636 | 2/20 | 0.49 |
| ▸ | PKM | P14618 | 2/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | KDM4C | Q9H3R0 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | SIRT6 | Q8N6T7 | 2/20 | 0.45 |
| ▸ | P2RX1 | P51575 | 2/20 | 0.45 |
| ▸ | P2RX4 | Q99571 | 1/20 | 0.45 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.45 |
| ▸ | PTPN5 | P54829 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23796662 | 1.00 | AKR1C3 (0.52) | AKR1C3AKR1C2AKR1C1HSD17B10MAPT | |
| SCHEMBL23796947 | 0.92 | PKM (0.49) | AKR1C3AKR1C2AKR1C1HSD17B10MAPT | |
| SCHEMBL23796721 | 0.90 | KMT2A (0.57) | AKR1C3AKR1C2AKR1C1HSD17B10MAPT | |
| SCHEMBL23796624 | 0.87 | AKR1C3 (0.64) | AKR1C3AKR1C2AKR1C1HSD17B10MAPT | |
| SCHEMBL30032740 | 0.87 | AKR1C3 (0.64) | AKR1C3AKR1C2AKR1C1HSD17B10MAPT | |
| SCHEMBL23796439 | 0.87 | AKR1C3 (0.64) | AKR1C3AKR1C2AKR1C1HSD17B10MAPT | |
| SCHEMBL30032694 | 0.86 | SNCA (0.50) | HSD17B10PKMPOLBHPGDKMT2A | |
| SCHEMBL23796514 | 0.86 | SNCA (0.50) | HSD17B10PKMPOLBHPGDKMT2A | |
| SCHEMBL23796665 | 0.85 | KMT2A (0.48) | HSD17B10PKMPOLBKDM4EKMT2A | |
| SCHEMBL23796489 | 0.83 | SNCA (0.50) | PKMPOLBKMT2AP2RX1P2RX4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115279730-A | 2, 5-or 2, 6-disubstituted hydroquinone derivatives having at least one carboxyl, sulfo or amido group useful as medicaments | OM药物公司 | 2022-11-01 | — | — | CN | claimed |