Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.38 |
| ▸ | MERTK | Q12866 | 1/20 | 0.37 |
| ▸ | MET | P08581 | 3/20 | 0.36 |
| ▸ | AXL | P30530 | 3/20 | 0.35 |
| ▸ | MGLL | Q99685 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23749566 | 1.00 | ALDH1A1 (0.41) | ALDH1A1ALOX15KMT2ANOTUMMERTK | |
| SCHEMBL23071294 | 0.88 | NOTUM (0.48) | ALDH1A1KMT2ANOTUMMERTKMET | |
| SCHEMBL29814279 | 0.88 | NOTUM (0.48) | ALDH1A1KMT2ANOTUMMERTKMET | |
| SCHEMBL29625547 | 0.87 | KMT2A (0.43) | ALDH1A1KMT2ANOTUMMERTKMET | |
| SCHEMBL22511513 | 0.80 | AXL (0.47) | MERTKMETAXL | |
| SCHEMBL23749378 | 0.79 | AXL (0.46) | ALDH1A1NOTUMMERTKMETAXL | |
| SCHEMBL23749475 | 0.76 | AXL (0.38) | ALDH1A1KMT2ANOTUMMERTKMET | |
| SCHEMBL23749506 | 0.76 | AXL (0.40) | ALDH1A1KMT2ANOTUMMERTKMET | |
| SCHEMBL31091475 | 0.75 | NOTUM (0.49) | ALDH1A1ALOX15KMT2ANOTUM | |
| SCHEMBL30672106 | 0.73 | MERTK (0.43) | ALDH1A1ALOX15KMT2AMERTKMET |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111196814-B | Aromatic ring-linked dioxane quinazoline or quinoline compound, composition and application thereof | 北京赛特明强医药科技有限公司 | 2022-12-06 | — | — | CN | disclosed |