Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CA | P42336 | 1/20 | 0.38 |
| ▸ | FYN | P06241 | 3/20 | 0.37 |
| ▸ | MAP3K12 | Q12852 | 7/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | ALK | Q9UM73 | 2/20 | 0.34 |
| ▸ | PDE2A | O00408 | 1/20 | 0.34 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.34 |
| ▸ | CSF1R | P07333 | 1/20 | 0.34 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.34 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.34 |
| ▸ | P2RX3 | P56373 | 1/20 | 0.34 |
| ▸ | P2RX2 | Q9UBL9 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23641248 | 1.00 | PIK3CA (0.38) | PIK3CAFYNMAP3K12POLBALK | |
| SCHEMBL27314054 | 0.86 | MAP3K12 (0.42) | MAP3K12 | |
| SCHEMBL2901554 | 0.81 | FYN (0.45) | FYNALDH1A1CYP3A4TLR8P2RX3 | |
| SCHEMBL30723495 | 0.80 | SCN9A (0.38) | FYNHCRTR1HCRTR2 | |
| SCHEMBL23641518 | 0.80 | SCN9A (0.38) | FYNHCRTR1HCRTR2 | |
| SCHEMBL24696640 | 0.77 | MAP4K4 (0.34) | PIK3CAMAP3K12 | |
| SCHEMBL16416412 | 0.73 | PIK3CA (0.42) | PIK3CAFYNALDH1A1 | |
| SCHEMBL24588295 | 0.72 | PIK3C3 (0.38) | PIK3CAMAP3K12POLBP2RX3P2RX2 | |
| SCHEMBL2121662 | 0.72 | FYN (0.45) | FYNALKTLR8P2RX3P2RX2 | |
| SCHEMBL10174184 | 0.71 | NOS3 (0.48) | MAP3K12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112292375-B | Substituted alkoxypyridinyl indole sulfonamides | 优时比制药有限公司 | 2023-12-05 | — | — | CN | disclosed |
| WO-2022214937-A1 | SUBSTITUTED TETRACYCLIC CARBOXYLIC ACIDS, ANALOGUES THEREOF, AND METHODS USING SAME | ARBUTUS BIOPHARMA CORPORATION (CA) | 2022-10-13 | — | — | WO | disclosed |