Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.42 |
| ▸ | ATR | Q13535 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | CCNE1 | P24864 | 1/20 | 0.39 |
| ▸ | CDK2 | P24941 | 1/20 | 0.39 |
| ▸ | MTOR | P42345 | 1/20 | 0.39 |
| ▸ | CNR1 | P21554 | 1/20 | 0.38 |
| ▸ | SNCA | P37840 | 2/20 | 0.37 |
| ▸ | HPN | P05981 | 1/20 | 0.37 |
| ▸ | CECR2 | Q9BXF3 | 1/20 | 0.36 |
| ▸ | S1PR1 | P21453 | 2/20 | 0.36 |
| ▸ | CTSA | P10619 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 2/20 | 0.35 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.35 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.35 |
| ▸ | PPARG | P37231 | 1/20 | 0.35 |
| ▸ | NCOA2 | Q15596 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30032460 | 0.85 | KDM4E (0.58) | ALDH1A1PDK2ATRMAPTKDM4E | |
| SCHEMBL30032117 | 0.84 | PIK3CA (0.39) | ALDH1A1MTORSNCAS1PR1LIPC | |
| Hydrochloric Acid SCHEMBL30032111 | 0.76 | PDK2 (0.35) | ALDH1A1PDK2ATRMAPTKDM4E | |
| Hydrochloric Acid SCHEMBL30031488 | 0.76 | GSK3B (0.37) | ALDH1A1PDK2ATRKDM4ECCNE1 | |
| Hydrochloric Acid SCHEMBL30031687 | 0.75 | S1PR1 (0.41) | PDK2ATRCCNE1CDK2MTOR | |
| SCHEMBL4500590 | 0.73 | ALDH1A1 (0.74) | ALDH1A1PDK2MAPTKDM4EHPGD | |
| SCHEMBL30032697 | 0.72 | ALDH1A1 (0.51) | ALDH1A1PDK2ATRKDM4ECCNE1 | |
| SCHEMBL10331346 | 0.70 | PDK2 (0.47) | ALDH1A1PDK2ATRMAPTKDM4E | |
| SCHEMBL30031653 | 0.69 | MGAM (0.48) | ALDH1A1MAPTKDM4EL3MBTL1MTOR | |
| SCHEMBL9653150 | 0.69 | ALDH1A1 (0.60) | ALDH1A1MAPTKDM4EL3MBTL1CNR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220363662-A1 | COMPOUNDS AS LXR AGONISTS | Integral Biosciences Privated Limited (IN) | 2022-11-17 | — | — | US | disclosed |
| WO-2022224166-A1 | COMPOUNDS AS LXR AGONISTS | INTEGRAL BIOSCIENCES PRIVATE LIMITED (IN) | 2022-10-27 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220363662-A1 | COMPOUNDS AS LXR AGONISTS | NR1H2, NR1H3, NR1H4 | ALDH1A1 781/4885PDK2 1088/4885ATR 2130/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.