Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2C | P28335 | 6/20 | 0.53 |
| ▸ | PDE2A | O00408 | 2/20 | 0.48 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.47 |
| ▸ | BCDIN3D | Q7Z5W3 | 8/20 | 0.45 |
| ▸ | HRH1 | P35367 | 1/20 | 0.43 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.43 |
| ▸ | CA1 | P00915 | 1/20 | 0.42 |
| ▸ | CA2 | P00918 | 1/20 | 0.42 |
| ▸ | CA9 | Q16790 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23579785 | 1.00 | HTR2C (0.53) | HTR2CPDE2APIK3CABCDIN3DHRH1 | |
| SCHEMBL30034965 | 0.92 | HTR2C (0.53) | HTR2CPDE2ABCDIN3DHRH1HRH4 | |
| SCHEMBL23579669 | 0.92 | HTR2C (0.53) | HTR2CPDE2ABCDIN3DHRH1HRH4 | |
| SCHEMBL23598905 | 0.90 | HTR2C (0.54) | HTR2CPDE2APIK3CABCDIN3DCA1 | |
| SCHEMBL30034770 | 0.90 | HTR2C (0.54) | HTR2CPDE2APIK3CABCDIN3DCA1 | |
| SCHEMBL13943266 | 0.86 | HTR2C (0.58) | HTR2CPDE2APIK3CABCDIN3DHRH1 | |
| SCHEMBL13944350 | 0.85 | PDE2A (0.68) | HTR2CPDE2APIK3CABCDIN3DHRH1 | |
| SCHEMBL13944731 | 0.85 | HTR2C (0.72) | HTR2CPDE2APIK3CAHRH4 | |
| SCHEMBL3644693 | 0.83 | HTR2C (0.58) | HTR2CPDE2APIK3CABCDIN3DHRH1 | |
| SCHEMBL23579797 | 0.82 | PDE2A (0.55) | PDE2ABCDIN3DCA1CA2CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115151550-B | External nucleotide pyrophosphatase/phosphodiesterase 1 (ENPP 1) modulators and uses thereof | 桑福德·伯纳姆·普雷比医学发现研究所 | 2024-11-22 | — | — | CN | disclosed |
| EP-4081528-A1 | ECTONUCLEOTIDE PYROPHOSPHATASE/PHOSPHODIESTERASE 1 (ENPP1) MODULATORS AND USES THEREOF | Sanford Burnham Prebys Medical Discovery Institute (US) | 2022-11-02 | — | — | EP | disclosed |