Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PSMD14 | O00487 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | CA1 | P00915 | 15/20 | 0.42 |
| ▸ | CA2 | P00918 | 15/20 | 0.42 |
| ▸ | CA9 | Q16790 | 15/20 | 0.42 |
| ▸ | CA12 | O43570 | 3/20 | 0.40 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.40 |
| ▸ | PDE2A | O00408 | 1/20 | 0.40 |
| ▸ | IKBKE | Q14164 | 1/20 | 0.40 |
| ▸ | TBK1 | Q9UHD2 | 1/20 | 0.40 |
| ▸ | CCNT1 | O60563 | 1/20 | 0.39 |
| ▸ | CDK9 | P50750 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23599082 | 1.00 | PSMD14 (0.47) | PSMD14L3MBTL1CA1CA2CA9 | |
| SCHEMBL23598884 | 0.84 | CA1 (0.47) | CA1CA2CA9CA12CA14 | |
| SCHEMBL30035122 | 0.83 | CA1 (0.48) | CA1CA2CA9CA12CA14 | |
| SCHEMBL23579835 | 0.83 | CA1 (0.48) | CA1CA2CA9CA12CA14 | |
| SCHEMBL23580338 | 0.82 | CA1 (0.50) | CA1CA2CA9CA12CA14 | |
| SCHEMBL28855384 | 0.82 | CA1 (0.40) | CA1CA2CA9CCNT1CDK9 | |
| SCHEMBL23579985 | 0.82 | CA1 (0.43) | CA1CA2CA9CA12CA14 | |
| SCHEMBL30033327 | 0.82 | CA1 (0.52) | CA1CA2CA9CA12CA14 | |
| SCHEMBL23580288 | 0.82 | CA1 (0.52) | CA1CA2CA9CA12CA14 | |
| SCHEMBL23598992 | 0.80 | CA1 (0.53) | CA1CA2CA9CA12CA14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115151550-B | External nucleotide pyrophosphatase/phosphodiesterase 1 (ENPP 1) modulators and uses thereof | 桑福德·伯纳姆·普雷比医学发现研究所 | 2024-11-22 | — | — | CN | disclosed |
| EP-4081528-A1 | ECTONUCLEOTIDE PYROPHOSPHATASE/PHOSPHODIESTERASE 1 (ENPP1) MODULATORS AND USES THEREOF | Sanford Burnham Prebys Medical Discovery Institute (US) | 2022-11-02 | — | — | EP | disclosed |