Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | MAP3K14 | Q99558 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | PARP1 | P09874 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
| ▸ | RECQL | P46063 | 1/20 | 0.31 |
| ▸ | BLM | P54132 | 1/20 | 0.31 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5653476 | 0.79 | LMNA (0.43) | LMNAMAP3K14KDM4EPOLBCYP3A4 | |
| SCHEMBL30034979 | 0.76 | NOTUM (0.41) | LMNAMAP3K14KDM4EPOLBCYP3A4 | |
| SCHEMBL22528183 | 0.73 | LMNA (0.42) | LMNAMAP3K14KDM4EPOLBCYP3A4 | |
| SCHEMBL19691122 | 0.72 | LMNA (0.41) | LMNAMAP3K14KDM4EPARP1TSHR | |
| SCHEMBL27873870 | 0.72 | LMNA (0.45) | LMNAMAP3K14KDM4EPOLBCYP3A4 | |
| SCHEMBL1269750 | 0.69 | — | — | |
| SCHEMBL1396053 | 0.68 | LMNA (0.38) | LMNAMAP3K14KDM4EPOLBCYP3A4 | |
| SCHEMBL22528179 | 0.67 | LMNA (0.35) | LMNAMAP3K14KDM4ECYP2C19 | |
| SCHEMBL308631 | 0.67 | — | — | |
| SCHEMBL18193495 | 0.67 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109153640-B | Eliminating hepatitis B virus with antiviral agent | 埃默里大学 | 2022-10-28 | — | — | CN | disclosed |