SCHEMBL30034871

SCHEMBL30034871

OC1(c2nc3ccc(Cl)cc3s2)CCCC1

nearest known ligand 0.49

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NPC1 O15118 8/20 0.48
RAB9A P51151 8/20 0.48
SMN1; SMN2 Q16637 4/20 0.48
MAPT P10636 2/20 0.45
ALDH1A1 P00352 2/20 0.45
KDM4E B2RXH2 1/20 0.45
MEN1 O00255 1/20 0.45
LMNA P02545 1/20 0.45
GAA P10253 1/20 0.45
ALOX12 P18054 1/20 0.45
HTT P42858 1/20 0.45
KMT2A Q03164 1/20 0.45
CASP3 P42574 5/20 0.44
SENP8 Q96LD8 5/20 0.44
SENP7 Q9BQF6 5/20 0.44
SENP6 Q9GZR1 5/20 0.44
DYRK1A Q13627 1/20 0.43
FSCN1 Q16658 1/20 0.43
CLK1 P49759 1/20 0.41
APP P05067 2/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30036653 0.98 NPC1 (0.50) NPC1RAB9ASMN1; SMN2MAPTALDH1A1
SCHEMBL29690499 0.97 NPC1 (0.48) NPC1RAB9ASMN1; SMN2MAPTALDH1A1
SCHEMBL4908372 0.78 CASR (0.50) NPC1RAB9ASMN1; SMN2MAPTALDH1A1
SCHEMBL29690713 0.76 CASR (0.49) NPC1RAB9ASMN1; SMN2MAPTALDH1A1
SCHEMBL25320313 0.75 NPC1 (0.51) NPC1RAB9ASMN1; SMN2MAPTMEN1
SCHEMBL14893967 0.75 NPC1 (0.45) NPC1RAB9ASMN1; SMN2MAPTALDH1A1
SCHEMBL25322228 0.73 SMN1; SMN2 (0.43) NPC1RAB9ASMN1; SMN2PPARA
SCHEMBL30731297 0.73 NPC1 (0.43) NPC1RAB9ASMN1; SMN2MAPTALDH1A1
SCHEMBL29895642 0.73 NPC1 (0.49) NPC1RAB9ASMN1; SMN2MAPTALDH1A1
SCHEMBL16835605 0.73 L3MBTL1 (0.42) NPC1RAB9ASMN1; SMN2HTTDYRK1A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115246798-A Method for synthesizing photocatalytic beta-C heteroaryl substituted alcohol 浙江工业大学 2022-10-28 CN disclosed