Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 1/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | POLB | P06746 | 2/20 | 0.44 |
| ▸ | HPGD | P15428 | 2/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.43 |
| ▸ | HTT | P42858 | 2/20 | 0.43 |
| ▸ | CA12 | O43570 | 2/20 | 0.42 |
| ▸ | CA9 | Q16790 | 2/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.41 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | NPY5R | Q15761 | 2/20 | 0.40 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.40 |
| ▸ | CA1 | P00915 | 1/20 | 0.40 |
| ▸ | CA2 | P00918 | 1/20 | 0.40 |
| ▸ | CA7 | P43166 | 1/20 | 0.40 |
| ▸ | XDH | P47989 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8004920 | 1.00 | ALOX5 (0.54) | ALOX5ALDH1A1KDM4ESMN1; SMN2LMNA | |
| SCHEMBL24306812 | 0.95 | ALOX5 (0.52) | ALOX5ALDH1A1KDM4ESMN1; SMN2LMNA | |
| SCHEMBL24306807 | 0.95 | ALOX5 (0.52) | ALOX5ALDH1A1KDM4ESMN1; SMN2LMNA | |
| SCHEMBL24306397 | 0.94 | ALOX5 (0.51) | ALOX5ALDH1A1KDM4ESMN1; SMN2LMNA | |
| SCHEMBL24307068 | 0.92 | ALOX5 (0.50) | ALOX5ALDH1A1KDM4ESMN1; SMN2LMNA | |
| SCHEMBL24306786 | 0.90 | ALOX5 (0.52) | ALOX5ALDH1A1KDM4ESMN1; SMN2LMNA | |
| SCHEMBL24306342 | 0.90 | ALOX5 (0.52) | ALOX5ALDH1A1KDM4ESMN1; SMN2LMNA | |
| SCHEMBL24306851 | 0.90 | ALOX5 (0.52) | ALOX5ALDH1A1KDM4ESMN1; SMN2LMNA | |
| SCHEMBL24307094 | 0.88 | ALOX5 (0.51) | ALOX5ALDH1A1KDM4ESMN1; SMN2LMNA | |
| SCHEMBL24307595 | 0.88 | ALOX5 (0.51) | ALOX5ALDH1A1KDM4ESMN1; SMN2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2026087635-A1 | DIHYDRO BENZOXAZINE DERIVATIVES | F. HOFFMANN-LA ROCHE AG (CH) | 2026-04-30 | — | — | WO | disclosed |
| WO-2025262003-A1 | DIHYDRO BENZOXAZINE DERIVATIVES | F. HOFFMANN-LA ROCHE AG (CH) | 2025-12-26 | — | — | WO | disclosed |
| CN-115605476-A | Substituted tricyclic compounds | 鲁宾有限公司（IN） | 2023-01-13 | — | — | CN | disclosed |
| EP-4081521-A1 | SUBSTITUTED TRICYCLIC COMPOUNDS | Lupin Limited (IN) | 2022-11-02 | — | — | EP | disclosed |