SCHEMBL30036611

SCHEMBL30036611

O/N=C\c1ccc(-c2ccc(O)c(F)c2)c(Cl)c1O

nearest known ligand 0.47

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
ESR1 P03372 13/20 0.47
ESR2 Q92731 13/20 0.47
CA12 O43570 1/20 0.47
CA1 P00915 1/20 0.47
CA2 P00918 1/20 0.47
CA9 Q16790 1/20 0.47
MGLL Q99685 5/20 0.38
HSD17B1 P14061 2/20 0.37
HSD17B2 P37059 1/20 0.36
KDM4E B2RXH2 1/20 0.35
LMNA P02545 1/20 0.35
HSD17B10 Q99714 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29576668 1.00 ESR1 (0.47) ESR1ESR2CA12CA1CA2
SCHEMBL17353846 1.00 ESR1 (0.47) ESR1ESR2CA12CA1CA2
SCHEMBL15542687 1.00 ESR1 (0.47) ESR1ESR2CA12CA1CA2
SCHEMBL4898311 0.90 ESR1 (0.48) ESR1ESR2CA12CA1CA2
SCHEMBL4898305 0.90 ESR1 (0.48) ESR1ESR2CA12CA1CA2
SCHEMBL22309433 0.83 ERN1 (0.46) ESR1ESR2CA12CA1CA2
SCHEMBL4897806 0.80 HSD17B1 (0.50) ESR1ESR2MGLLHSD17B1HSD17B2
SCHEMBL4897802 0.80 HSD17B1 (0.50) ESR1ESR2MGLLHSD17B1HSD17B2
SCHEMBL22309431 0.79 ESR1 (0.43) ESR1ESR2CA12CA1CA2
SCHEMBL5153007 0.79 GCGR (0.47) ESR1ESR2MGLLHSD17B1HSD17B2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250230416-A1 MULTI DONOR STEM CELL COMPOSITIONS AND METHODS OF MAKING SAME CHILDREN'S HOSPITAL MEDICAL CENTER (US) 2025-07-17 US disclosed
US-12281334-B2 Multi donor stem cell compositions and methods of making same CHILDREN'S HOSPITAL MEDICAL CENTER (US) 2025-04-22 US disclosed
US-20250092358-A1 In Vitro Breeding Systems and Methods in Livestock ABS GLOBAL, INC. (US) 2025-03-20 US disclosed
EP-4346395-A1 IN VITRO BREEDING SYSTEMS AND METHODS IN LIVESTOCK ABS Global, Inc. (US) 2024-04-10 EP disclosed
CN-117412668-A Livestock in vitro breeding system and method ABS全球公司 2024-01-16 CN disclosed
WO-2022251549-A1 IN VITRO BREEDING SYSTEMS AND METHODS IN LIVESTOCK ABS GLOBAL, INC. (US) 2022-12-01 WO disclosed