Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TTR | P02766 | 1/20 | 0.43 |
| ▸ | DPP4 | P27487 | 1/20 | 0.43 |
| ▸ | CA12 | O43570 | 1/20 | 0.42 |
| ▸ | CA1 | P00915 | 1/20 | 0.42 |
| ▸ | CA2 | P00918 | 1/20 | 0.42 |
| ▸ | CA7 | P43166 | 1/20 | 0.42 |
| ▸ | CA9 | Q16790 | 1/20 | 0.42 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.42 |
| ▸ | CNKSR1 | Q969H4 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | MAOB | P27338 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | FDPS | P14324 | 1/20 | 0.38 |
| ▸ | P2RY12 | Q9H244 | 1/20 | 0.37 |
| ▸ | CCNC | P24863 | 1/20 | 0.37 |
| ▸ | CDK8 | P49336 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20223478 | 1.00 | TTR (0.43) | TTRDPP4CA12CA1CA2 | |
| SCHEMBL20223056 | 0.79 | KDM4E (0.41) | KDM4EKMT2ASMN1; SMN2MAPTALDH1A1 | |
| SCHEMBL12498091 | 0.78 | CYP3A4 (0.56) | TTRDPP4CA12CA1CA2 | |
| SCHEMBL9515240 | 0.78 | CYP3A4 (0.56) | TTRDPP4CA12CA1CA2 | |
| SCHEMBL20212171 | 0.77 | KDM4E (0.39) | KDM4EKMT2AMAPTHCAR2RAB9A | |
| SCHEMBL29005510 | 0.77 | DPP4 (0.42) | TTRDPP4CA12CA1CA2 | |
| SCHEMBL29363532 | 0.77 | DPP4 (0.42) | TTRDPP4CA12CA1CA2 | |
| SCHEMBL30036501 | 0.76 | TLR8 (0.53) | TTRDPP4CYP3A4 | |
| SCHEMBL20223479 | 0.76 | TLR8 (0.53) | TTRDPP4CYP3A4 | |
| SCHEMBL7174672 | 0.75 | LMNA (0.39) | TTRDPP4CA12CA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110177780-B | Pyrimidine compounds containing acidic groups | 阿普罗斯治疗公司 | 2022-11-01 | — | — | CN | disclosed |