Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TGM2 | P21980 | 1/20 | 0.66 |
| ▸ | KRAS | P01116 | 8/20 | 0.62 |
| ▸ | TAS1R3 | Q7RTX0 | 2/20 | 0.60 |
| ▸ | TAS1R1 | Q7RTX1 | 2/20 | 0.60 |
| ▸ | FUT5 | Q11128 | 1/20 | 0.59 |
| ▸ | NT5E | P21589 | 1/20 | 0.59 |
| ▸ | P2RY6 | Q15077 | 2/20 | 0.57 |
| ▸ | P2RY2 | P41231 | 1/20 | 0.57 |
| ▸ | P2RY4 | P51582 | 1/20 | 0.57 |
| ▸ | ENPP1 | P22413 | 2/20 | 0.56 |
| ▸ | P2RY1 | P47900 | 2/20 | 0.56 |
| ▸ | P2RY12 | Q9H244 | 1/20 | 0.56 |
| ▸ | P2RX1 | P51575 | 1/20 | 0.55 |
| ▸ | P2RX3 | P56373 | 1/20 | 0.55 |
| ▸ | P2RY11 | Q96G91 | 1/20 | 0.55 |
| ▸ | P2RX4 | Q99571 | 1/20 | 0.55 |
| ▸ | DCPS | Q96C86 | 1/20 | 0.54 |
| ▸ | RNASEL | Q05823 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29793878 | 0.90 | KRAS (0.64) | TGM2KRASTAS1R3TAS1R1FUT5 | |
| SCHEMBL29657998 | 0.90 | KRAS (0.65) | TGM2KRASTAS1R3TAS1R1FUT5 | |
| SCHEMBL5827788 | 0.89 | TGM2 (0.69) | TGM2KRASTAS1R3TAS1R1FUT5 | |
| SCHEMBL5827796 | 0.89 | TGM2 (0.69) | TGM2KRASTAS1R3TAS1R1FUT5 | |
| SCHEMBL26209880 | 0.89 | TGM2 (0.65) | TGM2KRASTAS1R3TAS1R1FUT5 | |
| SCHEMBL15747229 | 0.88 | TGM2 (0.68) | TGM2KRASTAS1R3TAS1R1FUT5 | |
| SCHEMBL29829660 | 0.88 | TGM2 (0.68) | TGM2KRASTAS1R3TAS1R1FUT5 | |
| SCHEMBL2030121 | 0.88 | TGM2 (0.68) | TGM2KRASTAS1R3TAS1R1FUT5 | |
| SCHEMBL3187816 | 0.88 | TGM2 (0.68) | TGM2KRASTAS1R3TAS1R1FUT5 | |
| SCHEMBL23176397 | 0.88 | TGM2 (0.70) | TGM2KRASFUT5NT5EP2RY6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111393519-B | Novel stapled peptides as KRASG12C/SOS1 inhibitors and uses thereof | 中国药科大学 | 2022-11-08 | — | — | CN | disclosed |