Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 6/20 | 0.47 |
| ▸ | CNR1 | P21554 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL176661 | 0.89 | CNR2 (0.58) | CNR2CNR1 | |
| SCHEMBL176530 | 0.84 | CNR2 (0.56) | CNR2CNR1 | |
| SCHEMBL300521 | 0.78 | CNR2 (0.43) | CNR2 | |
| SCHEMBL10080083 | 0.78 | CNR2 (0.58) | CNR2CNR1 | |
| SCHEMBL257725 | 0.78 | CNR2 (0.43) | CNR2CNR1 | |
| SCHEMBL176569 | 0.77 | CNR2 (0.65) | CNR2CNR1 | |
| SCHEMBL3469566 | 0.76 | CNR2 (0.43) | CNR2CNR1 | |
| SCHEMBL300476 | 0.75 | CNR2 (0.55) | CNR2CNR1 | |
| SCHEMBL300469 | 0.74 | CYP3A4 (0.40) | CNR2 | |
| SCHEMBL176977 | 0.74 | CNR2 (0.53) | CNR2CNR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1937259-B1 | HEXAHYDRO-CYCLOHEPTAPYRAZOLE CANNABINOID MODULATORS | JANSSEN PHARMACEUTICA NV (BE) | 2011-11-23 | — | — | EP | claimed |