Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 6/20 | 0.69 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.69 |
| ▸ | NPC1 | O15118 | 3/20 | 0.58 |
| ▸ | RAB9A | P51151 | 3/20 | 0.58 |
| ▸ | CXCR2 | P25025 | 1/20 | 0.54 |
| ▸ | POLB | P06746 | 3/20 | 0.52 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.52 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.52 |
| ▸ | KCNK3 | O14649 | 1/20 | 0.52 |
| ▸ | KCNK9 | Q9NPC2 | 1/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.52 |
| ▸ | KDM1A | O60341 | 1/20 | 0.52 |
| ▸ | MAOB | P27338 | 1/20 | 0.52 |
| ▸ | HTR2B | P41595 | 1/20 | 0.52 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.51 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | MITF | O75030 | 1/20 | 0.49 |
| ▸ | TP53 | P04637 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1696431 | 0.87 | MEN1 (0.68) | MEN1KMT2ANPC1RAB9ACXCR2 | |
| SCHEMBL29994466 | 0.87 | HDAC8 (0.59) | MEN1KMT2ANPC1RAB9APOLB | |
| SCHEMBL15676725 | 0.84 | MEN1 (0.71) | MEN1KMT2ANPC1RAB9ACXCR2 | |
| SCHEMBL8867655 | 0.82 | PTPN1 (0.65) | MEN1KMT2ANPC1RAB9APOLB | |
| SCHEMBL1690510 | 0.81 | MEN1 (0.66) | MEN1KMT2ANPC1RAB9ACXCR2 | |
| SCHEMBL30739642 | 0.80 | KMT2A (0.86) | MEN1KMT2ANPC1RAB9APOLB | |
| SCHEMBL19157408 | 0.78 | MEN1 (0.51) | MEN1KMT2ANPC1RAB9AKDM1A | |
| SCHEMBL10804897 | 0.77 | MEN1 (0.81) | MEN1KMT2ANPC1RAB9APOLB | |
| SCHEMBL3992218 | 0.76 | KMT2A (0.57) | MEN1KMT2ANPC1RAB9APOLB | |
| SCHEMBL7235790 | 0.76 | MEN1 (0.84) | MEN1KMT2ANPC1RAB9APOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4096661-A1 | COMPOUNDS AND COMPOSITIONS FOR USE IN TREATING SKIN DISORDERS | Kamari Pharma Ltd. (IL) | 2022-12-07 | — | — | EP | disclosed |