Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.51 |
| ▸ | HTR2A | P28223 | 3/20 | 0.51 |
| ▸ | HTR2C | P28335 | 1/20 | 0.51 |
| ▸ | HTR7 | P34969 | 1/20 | 0.51 |
| ▸ | HTR6 | P50406 | 1/20 | 0.51 |
| ▸ | CCR3 | P51677 | 3/20 | 0.50 |
| ▸ | HTR2B | P41595 | 1/20 | 0.48 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | TP53 | P04637 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | ACKR3 | P25106 | 1/20 | 0.46 |
| ▸ | HTR1A | P08908 | 1/20 | 0.46 |
| ▸ | HTR1D | P28221 | 1/20 | 0.46 |
| ▸ | HTR1B | P28222 | 1/20 | 0.46 |
| ▸ | KDM1A | O60341 | 1/20 | 0.46 |
| ▸ | MAOB | P27338 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21844837 | 0.81 | HTR2A (0.47) | HTR2AHTR2CHTR7HTR6NPC1 | |
| SCHEMBL21844944 | 0.80 | HTR1A (0.54) | MEN1KMT2AHTR2AHTR2CHTR7 | |
| SCHEMBL19157261 | 0.80 | ACKR3 (0.49) | MEN1KMT2AHTR2AHTR2CHTR7 | |
| SCHEMBL30037664 | 0.78 | MEN1 (0.69) | MEN1KMT2AHTR2BNPC1TP53 | |
| SCHEMBL20083898 | 0.78 | KDR (0.44) | MEN1KMT2AHTR2AHTR2CHTR7 | |
| SCHEMBL15276863 | 0.78 | SMN1; SMN2 (0.59) | MEN1KMT2ANPC1ALDH1A1SMN1; SMN2 | |
| SCHEMBL21844836 | 0.77 | ACKR3 (0.51) | MEN1KMT2AHTR2AHTR2CHTR7 | |
| SCHEMBL19157902 | 0.76 | RORC (0.51) | MEN1KMT2AHTR2AHTR2CHTR7 | |
| SCHEMBL2561586 | 0.75 | HTR2A (0.61) | HTR2AHTR2CHTR7HTR6 | |
| SCHEMBL19157407 | 0.75 | HTR1A (0.56) | HTR2AHTR2CHTR7HTR2BNPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2794565-B1 | HEPATITIS B ANTIVIRAL AGENTS | NOVIRA THERAPEUTICS INC (US) | 2017-07-26 | — | — | EP | disclosed |