Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCL1 | Q07820 | 1/20 | 0.33 |
| ▸ | GRM8 | O00222 | 1/20 | 0.33 |
| ▸ | GRM6 | O15303 | 1/20 | 0.33 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.33 |
| ▸ | GRM3 | Q14832 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26444852 | 0.82 | MCL1 (0.32) | MCL1 | |
| SCHEMBL15659971 | 0.79 | TLR4 (0.34) | — | |
| SCHEMBL4611943 | 0.79 | — | — | |
| SCHEMBL29980746 | 0.78 | GRM8 (0.34) | GRM8GRM6GRM2GRM3ALDH1A1 | |
| SCHEMBL4836260 | 0.77 | — | — | |
| SCHEMBL1415539 | 0.76 | GRM8 (0.39) | GRM8GRM6GRM2GRM3POLB | |
| SCHEMBL1238701 | 0.74 | BRD4 (0.42) | ALDH1A1 | |
| SCHEMBL27704741 | 0.74 | GRM8 (0.38) | GRM8GRM6GRM2GRM3POLB | |
| Cyclopropane SCHEMBL7196796 | 0.74 | GRM8 (0.38) | MCL1GRM8GRM6GRM2GRM3 | |
| SCHEMBL1069345 | 0.72 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108025071-B | Dual variable domain immunoconjugates and uses thereof | 斯克利普斯研究院 | 2022-11-01 | — | — | CN | disclosed |