Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM8 | O00222 | 2/20 | 0.34 |
| ▸ | GRM6 | O15303 | 2/20 | 0.34 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.34 |
| ▸ | GRM3 | Q14832 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | GRM4 | Q14833 | 4/20 | 0.30 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.30 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.30 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.30 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.30 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.30 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4611943 | 0.81 | — | — | |
| SCHEMBL1415539 | 0.78 | GRM8 (0.39) | GRM8GRM6GRM2GRM3ALDH1A1 | |
| SCHEMBL30037802 | 0.78 | MCL1 (0.33) | GRM8GRM6GRM2GRM3ALDH1A1 | |
| SCHEMBL8058732 | 0.76 | MCL1 (0.32) | GAAKDM4E | |
| SCHEMBL27704741 | 0.76 | GRM8 (0.38) | GRM8GRM6GRM2GRM3ALDH1A1 | |
| Cyclopropane SCHEMBL7196796 | 0.76 | GRM8 (0.38) | GRM8GRM6GRM2GRM3ALDH1A1 | |
| SCHEMBL9289233 | 0.74 | TSHR (0.35) | ALDH1A1MAPT | |
| SCHEMBL11305170 | 0.74 | CYP2D6 (0.33) | GRM8GRM6GRM2GRM3ALDH1A1 | |
| Succinic Acid SCHEMBL9421166 | 0.73 | LMNA (0.43) | GRM8GRM6GRM2GRM3ALDH1A1 | |
| SCHEMBL31405426 | 0.73 | BRD4 (0.39) | ALDH1A1CYP1A2KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108289931-B | 4' -substituted nucleoside reverse transcriptase inhibitors and preparation thereof | 默沙东公司 | 2022-10-11 | — | — | CN | disclosed |