Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.51 |
| ▸ | NPC1 | O15118 | 2/20 | 0.51 |
| ▸ | RAB9A | P51151 | 2/20 | 0.51 |
| ▸ | POLB | P06746 | 1/20 | 0.51 |
| ▸ | HTT | P42858 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 4/20 | 0.49 |
| ▸ | TP53 | P04637 | 2/20 | 0.49 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | KCNK3 | O14649 | 6/20 | 0.46 |
| ▸ | KCNK9 | Q9NPC2 | 6/20 | 0.46 |
| ▸ | GAA | P10253 | 3/20 | 0.46 |
| ▸ | PKM | P14618 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | GABRA1 | P14867 | 3/20 | 0.46 |
| ▸ | GABRB2 | P47870 | 3/20 | 0.46 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30039667 | 0.90 | SMN1; SMN2 (0.52) | ALDH1A1KDM4ESMN1; SMN2NPC1RAB9A | |
| SCHEMBL30038776 | 0.89 | MAPT (0.61) | ALDH1A1KDM4ESMN1; SMN2NPC1RAB9A | |
| SCHEMBL30039601 | 0.88 | MAPT (0.59) | ALDH1A1KDM4ESMN1; SMN2NPC1RAB9A | |
| SCHEMBL30040119 | 0.88 | KDM4E (0.67) | ALDH1A1KDM4ESMN1; SMN2NPC1RAB9A | |
| SCHEMBL30040826 | 0.88 | SMN1; SMN2 (0.48) | ALDH1A1KDM4ESMN1; SMN2NPC1RAB9A | |
| SCHEMBL30040616 | 0.86 | NPC1 (0.55) | ALDH1A1KDM4ESMN1; SMN2NPC1RAB9A | |
| SCHEMBL30040080 | 0.85 | RAB9A (0.47) | ALDH1A1KDM4ESMN1; SMN2NPC1RAB9A | |
| SCHEMBL30040189 | 0.81 | KDM4E (0.51) | KDM4ESMN1; SMN2NPC1RAB9APOLB | |
| SCHEMBL30039938 | 0.79 | KCNK3 (0.51) | ALDH1A1KDM4ESMN1; SMN2NPC1RAB9A | |
| SCHEMBL30039534 | 0.78 | NR1H4 (0.57) | ALDH1A1KDM4ESMN1; SMN2NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115261896-B | Synthesis method of 4' -alkylamino benzyl-3-imidazo [1,2-a ] pyridine derivative | 深圳职业技术学院 | 2024-08-30 | — | — | CN | disclosed |
| CN-115261896-A | Synthesis method of 4' -alkylaminobenzyl-3-imidazo [1,2-a ] pyridine derivative | 深圳职业技术学院 | 2022-11-01 | — | — | CN | disclosed |