Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BACE1 | P56817 | 2/20 | 0.57 |
| ▸ | CTSD | P07339 | 4/20 | 0.52 |
| ▸ | MME | P08473 | 3/20 | 0.51 |
| ▸ | ACE | P12821 | 3/20 | 0.51 |
| ▸ | CPA1 | P15085 | 3/20 | 0.51 |
| ▸ | ACE2 | Q9BYF1 | 3/20 | 0.51 |
| ▸ | CASP1 | P29466 | 1/20 | 0.49 |
| ▸ | CASP3 | P42574 | 1/20 | 0.49 |
| ▸ | CASP4 | P49662 | 1/20 | 0.49 |
| ▸ | CASP5 | P51878 | 1/20 | 0.49 |
| ▸ | CASP9 | P55211 | 1/20 | 0.49 |
| ▸ | CASP6 | P55212 | 1/20 | 0.49 |
| ▸ | CASP8 | Q14790 | 1/20 | 0.49 |
| ▸ | CASP10 | Q92851 | 1/20 | 0.49 |
| ▸ | GRB2 | P62993 | 2/20 | 0.48 |
| ▸ | MAGI3 | Q5TCQ9 | 1/20 | 0.47 |
| ▸ | KISS1R | Q969F8 | 2/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15765930 | 0.94 | BACE1 (0.53) | BACE1CTSDMMEACECPA1 | |
| SCHEMBL30819112 | 0.93 | BACE1 (0.56) | BACE1CTSDMMEACECPA1 | |
| SCHEMBL31307223 | 0.92 | BACE1 (0.63) | BACE1CTSDCASP1CASP3CASP4 | |
| SCHEMBL30117298 | 0.92 | BACE1 (0.64) | BACE1CTSDMMEACECPA1 | |
| SCHEMBL30001080 | 0.90 | BACE1 (0.55) | BACE1CTSDMME | |
| SCHEMBL31220207 | 0.90 | BACE1 (0.58) | BACE1CTSDMMEACECPA1 | |
| SCHEMBL30544642 | 0.89 | CTSD (0.56) | BACE1CTSDMMEACECPA1 | |
| SCHEMBL30051590 | 0.89 | ACE (0.64) | BACE1CTSDMMEACECPA1 | |
| SCHEMBL31672244 | 0.88 | NAALAD2 (0.55) | MME | |
| SCHEMBL5970501 | 0.88 | NAALAD2 (0.55) | MME |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117202924-A | Therapeutic regimens and methods for lowering blood glucose and/or body weight using GLP-1R and GCGR balance agonists | 斯皮特弗尔制药有限责任公司 | 2023-12-08 | — | — | CN | disclosed |
| CN-115427065-A | GLP-1R and GCGR agonists, formulations, and methods of use | 斯皮特弗尔制药有限责任公司 | 2022-12-02 | — | — | CN | disclosed |