Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOTUM | Q6P988 | 7/20 | 0.52 |
| ▸ | HTR2C | P28335 | 4/20 | 0.50 |
| ▸ | TRIM24 | O15164 | 3/20 | 0.49 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.45 |
| ▸ | HTR2A | P28223 | 2/20 | 0.43 |
| ▸ | HTR2B | P41595 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.43 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30038539 | 0.84 | HTR2C (0.58) | NOTUMHTR2CTRIM24HTR2AHTR2B | |
| SCHEMBL19411076 | 0.79 | LMNA (0.47) | LMNASMN1; SMN2S1PR1 | |
| SCHEMBL2207784 | 0.78 | NOTUM (0.57) | NOTUMTRIM24LMNASMN1; SMN2CYP11B1 | |
| SCHEMBL29963196 | 0.78 | NOTUM (0.57) | NOTUMTRIM24LMNASMN1; SMN2CYP11B1 | |
| SCHEMBL6101817 | 0.78 | NOTUM (0.57) | NOTUMHTR2CTRIM24LMNASMN1; SMN2 | |
| SCHEMBL22130748 | 0.78 | MAOB (0.41) | HTR2CSMN1; SMN2S1PR1 | |
| SCHEMBL20939536 | 0.78 | NOTUM (0.57) | NOTUMTRIM24LMNASMN1; SMN2CYP11B1 | |
| SCHEMBL19428003 | 0.77 | HTR2C (0.43) | HTR2CS1PR1HTR2AHTR2BCYP1A2 | |
| SCHEMBL30039456 | 0.76 | XIAP (0.58) | NOTUMHTR2CLMNASMN1; SMN2 | |
| SCHEMBL30038735 | 0.75 | HTR2C (0.55) | HTR2CLMNAHTR2AHTR2BCYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110461831-B | Substituted indoline derivatives as inhibitors of dengue virus replication | 杨森制药公司 | 2022-11-01 | — | — | CN | disclosed |