Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC22A12 | Q96S37 | 8/20 | 0.57 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.52 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.52 |
| ▸ | HCAR3 | P49019 | 1/20 | 0.51 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | KMO | O15229 | 1/20 | 0.43 |
| ▸ | TTR | P02766 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | GRM1 | Q13255 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.41 |
| ▸ | QPCT | Q16769 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4509480 | 1.00 | SLC22A12 (0.57) | SLC22A12ADORA2AADORA2BHCAR3TDP1 | |
| SCHEMBL23535727 | 0.87 | HCAR3 (0.55) | SLC22A12ADORA2AADORA2BHCAR3TDP1 | |
| SCHEMBL30040739 | 0.87 | HCAR3 (0.55) | SLC22A12ADORA2AADORA2BHCAR3TDP1 | |
| SCHEMBL24759277 | 0.87 | ADORA2A (0.52) | SLC22A12ADORA2AADORA2BKDM4EKMO | |
| SCHEMBL22445956 | 0.85 | ADORA2A (0.50) | SLC22A12ADORA2AADORA2BKDM4EKMO | |
| SCHEMBL30987537 | 0.85 | ADORA2A (0.50) | SLC22A12ADORA2AADORA2BKDM4EKMO | |
| SCHEMBL17785249 | 0.83 | HCAR3 (0.47) | SLC22A12HCAR3KDM4E | |
| SCHEMBL23559707 | 0.83 | ADORA2A (0.47) | SLC22A12ADORA2AADORA2BTDP1KDM4E | |
| SCHEMBL29040312 | 0.83 | ADORA2A (0.47) | SLC22A12ADORA2AADORA2BHTTQPCT | |
| SCHEMBL23559591 | 0.82 | HCAR3 (0.46) | SLC22A12HCAR3TDP1KDM4EHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115427035-B | ENL/AF9 YEATS inhibitors | 洛克菲勒大学 | 2025-04-22 | — | — | CN | disclosed |
| CN-117858877-A | C-linked inhibitors of ENL/AF9 YEATS | 桥梁药品有限公司 | 2024-04-09 | — | — | CN | disclosed |
| CN-115427035-A | ENL/AF9YEATS inhibitors | 洛克菲勒大学 | 2022-12-02 | — | — | CN | disclosed |