Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LRRK2 | Q5S007 | 20/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20987207 | 1.00 | LRRK2 (0.48) | LRRK2 | |
| SCHEMBL30039324 | 0.83 | LRRK2 (0.41) | LRRK2 | |
| SCHEMBL17059353 | 0.81 | PIN1 (0.40) | LRRK2 | |
| SCHEMBL30040910 | 0.79 | KMT2A (0.41) | LRRK2 | |
| SCHEMBL30040637 | 0.79 | KMT2A (0.42) | LRRK2 | |
| SCHEMBL1356867 | 0.78 | LRRK2 (0.63) | LRRK2 | |
| SCHEMBL17670204 | 0.78 | LRRK2 (0.40) | LRRK2 | |
| SCHEMBL17059258 | 0.77 | EGFR (0.57) | LRRK2 | |
| SCHEMBL28378818 | 0.77 | EGFR (0.47) | — | |
| SCHEMBL26324590 | 0.77 | LRRK2 (0.39) | LRRK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113382991-B | Aminopyrimidines useful for inhibiting protein tyrosine kinase activity | 深圳市塔吉瑞生物医药有限公司 | 2022-12-27 | — | — | CN | disclosed |