SCHEMBL30040705

SCHEMBL30040705

ClCc1nc2ccc(Cl)cc2[nH]1

nearest known ligand 0.72

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 1/20 0.72
RAB9A P51151 2/20 0.59
ALDH1A1 P00352 3/20 0.58
HTR3E A5X5Y0 1/20 0.58
HTR3B O95264 1/20 0.58
HTR3A P46098 1/20 0.58
BACE1 P56817 1/20 0.58
HTR3D Q70Z44 1/20 0.58
HTR3C Q8WXA8 1/20 0.58
F10 P00742 1/20 0.56
IDO1 P14902 1/20 0.56
CYP1A2 P05177 1/20 0.54
CYP2D6 P10635 1/20 0.54
CYP2C9 P11712 1/20 0.54
CYP2C19 P33261 1/20 0.54
HPGD P15428 2/20 0.53
PSMB8 P28062 1/20 0.53
SMN1; SMN2 Q16637 1/20 0.53
EGFR P00533 4/20 0.52
ERBB2 P04626 2/20 0.52

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL656416 1.00 TDP1 (0.72) TDP1RAB9AALDH1A1HTR3EHTR3B
SCHEMBL485294 0.85 TDP1 (0.53) TDP1RAB9AALDH1A1HTR3EHTR3B
SCHEMBL29409142 0.84 TDP1 (0.70) TDP1RAB9AALDH1A1HTR3EHTR3B
SCHEMBL18291871 0.84 TDP1 (0.70) TDP1RAB9AALDH1A1HTR3EHTR3B
SCHEMBL8490941 0.84 TDP1 (0.70) TDP1RAB9AALDH1A1HTR3EHTR3B
SCHEMBL12636194 0.84 TDP1 (1.00) TDP1RAB9AALDH1A1HTR3EHTR3B
SCHEMBL4354084 0.84 TDP1 (0.70) TDP1RAB9AALDH1A1HTR3EHTR3B
SCHEMBL2407488 0.84 TDP1 (0.70) TDP1RAB9AALDH1A1HTR3EHTR3B
Hydrochloric Acid SCHEMBL31164757 0.82 TDP1 (0.68) TDP1RAB9AALDH1A1HTR3EHTR3B
Hydrochloric Acid SCHEMBL5204720 0.82 TDP1 (0.68) TDP1RAB9AALDH1A1HTR3EHTR3B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119775261-A Collagen 1 translation inhibitors and methods of use thereof 艾尼莫生物科技公司 2025-04-08 CN disclosed
CN-115427404-B Collagen 1 translation inhibitors and methods of use thereof 艾尼莫生物科技公司 2024-12-13 CN disclosed
CN-115427404-A Collagen 1 translation inhibitors and methods of use thereof 艾尼莫生物科技公司 2022-12-02 CN disclosed