Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TYR | P14679 | 4/20 | 0.50 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.46 |
| ▸ | WDR77 | Q9BQA1 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | PKM | P14618 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 3/20 | 0.44 |
| ▸ | RECQL | P46063 | 1/20 | 0.44 |
| ▸ | GRM5 | P41594 | 1/20 | 0.41 |
| ▸ | USP2 | O75604 | 1/20 | 0.41 |
| ▸ | GSK3B | P49841 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | CYP1B1 | Q16678 | 2/20 | 0.38 |
| ▸ | ALDH2 | P05091 | 1/20 | 0.37 |
| ▸ | ALDH3A1 | P30838 | 1/20 | 0.37 |
| ▸ | CASP3 | P42574 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23706172 | 1.00 | TYR (0.50) | TYRPRMT5WDR77ALDH1A1MEN1 | |
| SCHEMBL30041574 | 0.78 | MEN1 (0.49) | TYRPRMT5WDR77ALDH1A1MEN1 | |
| SCHEMBL23706090 | 0.78 | MEN1 (0.49) | TYRPRMT5WDR77ALDH1A1MEN1 | |
| SCHEMBL17293770 | 0.73 | MEN1 (0.64) | TYRPRMT5WDR77ALDH1A1MEN1 | |
| SCHEMBL6526615 | 0.72 | CYP1B1 (0.53) | TYRALDH1A1MEN1PKMKMT2A | |
| SCHEMBL8222291 | 0.71 | MEN1 (0.61) | TYRPRMT5WDR77ALDH1A1MEN1 | |
| SCHEMBL17979154 | 0.70 | GRM5 (0.51) | TYRPRMT5WDR77ALDH1A1MAPT | |
| SCHEMBL29411210 | 0.70 | GRM5 (0.51) | TYRPRMT5WDR77ALDH1A1MAPT | |
| SCHEMBL18562311 | 0.70 | PABPC1 (0.42) | ALDH1A1MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL23706036 | 0.70 | PABPC1 (0.42) | ALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115297861-B | Compounds and uses thereof | 福宏治疗公司 | 2024-07-12 | — | — | CN | disclosed |
| CN-115297861-A | Compound and use thereof | 福宏治疗公司 | 2022-11-04 | — | — | CN | disclosed |