Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | SNCA | P37840 | 1/20 | 0.40 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.39 |
| ▸ | GRIN2D | O15399 | 3/20 | 0.39 |
| ▸ | GRIN3B | O60391 | 3/20 | 0.39 |
| ▸ | GRIN1 | Q05586 | 3/20 | 0.39 |
| ▸ | GRIN2A | Q12879 | 3/20 | 0.39 |
| ▸ | GRIN2B | Q13224 | 3/20 | 0.39 |
| ▸ | GRIN2C | Q14957 | 3/20 | 0.39 |
| ▸ | GRIN3A | Q8TCU5 | 3/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.38 |
| ▸ | HIF1A | Q16665 | 3/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.37 |
| ▸ | TSHR | P16473 | 2/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.37 |
| ▸ | GMNN | O75496 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | PKM | P14618 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29186594 | 1.00 | MAPT (0.40) | MAPTSNCAHRH4GRIN2DGRIN3B | |
| SCHEMBL27924563 | 0.85 | GRIN2D (0.38) | MAPTSNCAHRH4GRIN2DGRIN3B | |
| SCHEMBL27943950 | 0.83 | GRIN2D (0.36) | MAPTSNCAHRH4GRIN2DGRIN3B | |
| SCHEMBL5676978 | 0.81 | HRH4 (0.39) | HRH4GRIN2DGRIN3BGRIN1GRIN2A | |
| SCHEMBL25375569 | 0.81 | ALDH1A1 (0.39) | MAPTGRIN2DGRIN3BGRIN1GRIN2A | |
| SCHEMBL30482195 | 0.81 | ALDH1A1 (0.39) | MAPTGRIN2DGRIN3BGRIN1GRIN2A | |
| SCHEMBL26451175 | 0.81 | ALDH1A1 (0.39) | MAPTGRIN2DGRIN3BGRIN1GRIN2A | |
| SCHEMBL25376372 | 0.81 | SMN1; SMN2 (0.39) | MAPTGRIN2DGRIN3BGRIN1GRIN2A | |
| SCHEMBL30482313 | 0.81 | SMN1; SMN2 (0.39) | MAPTGRIN2DGRIN3BGRIN1GRIN2A | |
| SCHEMBL5375525 | 0.79 | BRD4 (0.44) | MAPTSNCAHRH4GRIN2DGRIN3B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117321051-A | Compounds as PARP inhibitors | 重庆复尚源创医药技术有限公司 | 2023-12-29 | — | — | CN | disclosed |
| WO-2022228387-A1 | COMPOUNDS AS PARP INHIBITORS | FOCHON BIOSCIENCES, LTD. (CN) | 2022-11-03 | — | — | WO | disclosed |