SCHEMBL30041383

SCHEMBL30041383

NC(=O)Cc1ccc2[nH]c(CN3CCN(c4ccncc4)CC3)cc2c1

nearest known ligand 0.47

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
DRD4 P21917 8/20 0.47
DRD2 P14416 7/20 0.47
DRD3 P35462 7/20 0.47
SLC2A1 P11166 2/20 0.45
HTR1A P08908 1/20 0.44
ADRA2A P08913 1/20 0.44
ADRA2B P18089 1/20 0.44
ADRA2C P18825 1/20 0.44
OPRK1 P41145 1/20 0.44
SIRT1 Q96EB6 1/20 0.41
HDAC6 Q9UBN7 1/20 0.39
CHEK1 O14757 1/20 0.39
CDK7 P50613 1/20 0.39
SLC6A4 P31645 1/20 0.39
ITGB3 P05106 3/20 0.38
ITGA2B P08514 3/20 0.38
HRH3 Q9Y5N1 2/20 0.38
HRH4 Q9H3N8 1/20 0.38
AOC3 Q16853 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23964250 0.82 DRD2 (0.53) DRD4DRD2DRD3SLC2A1HTR1A
SCHEMBL23964260 0.81 DRD4 (0.54) DRD4DRD2DRD3SLC2A1HTR1A
SCHEMBL30041683 0.81 DRD4 (0.54) DRD4DRD2DRD3SLC2A1HTR1A
SCHEMBL23964265 0.81 DRD4 (0.54) DRD4DRD2DRD3SLC2A1HTR1A
SCHEMBL23964237 0.79 DRD2 (0.54) DRD4DRD2DRD3HTR1AADRA2A
SCHEMBL23964261 0.79 DRD4 (0.64) DRD4DRD2DRD3SLC2A1HTR1A
SCHEMBL23964226 0.78 DRD2 (0.47) DRD4DRD2DRD3SLC2A1HTR1A
SCHEMBL30041347 0.78 DRD2 (0.47) DRD4DRD2DRD3SLC2A1HTR1A
SCHEMBL25202850 0.78 PDGFRB (0.47) DRD4DRD2DRD3HTR1AADRA2A
Formic Acid SCHEMBL25187757 0.78 DRD4 (0.57) DRD4DRD2DRD3SLC2A1HTR1A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119775261-A Collagen 1 translation inhibitors and methods of use thereof 艾尼莫生物科技公司 2025-04-08 CN disclosed
CN-115427404-B Collagen 1 translation inhibitors and methods of use thereof 艾尼莫生物科技公司 2024-12-13 CN disclosed
CN-115427404-A Collagen 1 translation inhibitors and methods of use thereof 艾尼莫生物科技公司 2022-12-02 CN disclosed