SCHEMBL30041529

SCHEMBL30041529

Clc1ccc(-c2c(-c3ccc(Br)cc3)c(-c3ccccc3)c3c(c2-c2ccccc2)-c2cccc4cccc-3c24)cc1

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 6/20 0.42
MAPK1 P28482 3/20 0.42
CYP1A2 P05177 3/20 0.42
L3MBTL1 Q9Y468 2/20 0.38
TSHR P16473 2/20 0.38
HSD17B10 Q99714 2/20 0.38
ATM Q13315 1/20 0.38
KDM4E B2RXH2 4/20 0.38
LMNA P02545 2/20 0.38
GAA P10253 1/20 0.38
CYP2C9 P11712 2/20 0.36
CYP2C19 P33261 2/20 0.36
CYP3A4 P08684 1/20 0.36
CYP2D6 P10635 1/20 0.36
PSD A5PKW4 1/20 0.36
MAPK13 O15264 1/20 0.36
GCGR P47871 1/20 0.36
MAPK12 P53778 1/20 0.36
MAPK11 Q15759 1/20 0.36
MAPK14 Q16539 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24067757 1.00 ALDH1A1 (0.42) ALDH1A1MAPK1CYP1A2L3MBTL1TSHR
SCHEMBL728300 0.92 ALDH1A1 (0.50) ALDH1A1MAPK1L3MBTL1TSHRHSD17B10
SCHEMBL25864840 0.85 ALDH1A1 (0.50) ALDH1A1MAPK1CYP1A2L3MBTL1TSHR
SCHEMBL25864841 0.85 ALDH1A1 (0.50) ALDH1A1MAPK1CYP1A2L3MBTL1TSHR
SCHEMBL20161046 0.85 ALDH1A1 (0.50) ALDH1A1MAPK1CYP1A2L3MBTL1TSHR
SCHEMBL13085133 0.84 ALDH1A1 (0.45) ALDH1A1MAPK1CYP1A2L3MBTL1TSHR
SCHEMBL22143498 0.83 ALDH1A1 (0.61) ALDH1A1MAPK1CYP1A2L3MBTL1TSHR
SCHEMBL22143642 0.83 ALDH1A1 (0.61) ALDH1A1MAPK1CYP1A2L3MBTL1TSHR
SCHEMBL22143646 0.83 ALDH1A1 (0.61) ALDH1A1MAPK1CYP1A2L3MBTL1TSHR
SCHEMBL22143503 0.83 ALDH1A1 (0.61) ALDH1A1MAPK1CYP1A2L3MBTL1TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115279732-A Compound and organic light emitting device including the same 株式会社LG化学 2022-11-01 CN disclosed