Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRA1 | P14867 | 1/20 | 0.52 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.52 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.52 |
| ▸ | DYRK1A | Q13627 | 2/20 | 0.42 |
| ▸ | IDO1 | P14902 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | HPGDS | O60760 | 1/20 | 0.41 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.40 |
| ▸ | AAK1 | Q2M2I8 | 2/20 | 0.40 |
| ▸ | ATR | Q13535 | 1/20 | 0.40 |
| ▸ | ACVR2A | P27037 | 2/20 | 0.39 |
| ▸ | TGFBR2 | P37173 | 2/20 | 0.39 |
| ▸ | KCNT1 | Q5JUK3 | 1/20 | 0.38 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.38 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.38 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.38 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.38 |
| ▸ | LRRK2 | Q5S007 | 2/20 | 0.37 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL134768 | 0.81 | GABRA1 (0.53) | GABRA1GABRG2GABRB3DYRK1AAAK1 | |
| SCHEMBL30042134 | 0.81 | GABRA1 (0.53) | GABRA1GABRG2GABRB3DYRK1AAAK1 | |
| SCHEMBL132252 | 0.79 | GABRA1 (0.46) | GABRA1GABRG2GABRB3DYRK1AIDO1 | |
| SCHEMBL154945 | 0.79 | GABRA1 (0.49) | GABRA1GABRG2GABRB3DYRK1AIDO1 | |
| SCHEMBL23674461 | 0.75 | GABRA1 (0.51) | GABRA1GABRG2GABRB3DYRK1AGAA | |
| SCHEMBL30043057 | 0.75 | GABRA1 (0.51) | GABRA1GABRG2GABRB3DYRK1AIDO1 | |
| SCHEMBL30112252 | 0.75 | GABRA1 (0.51) | GABRA1GABRG2GABRB3DYRK1AGAA | |
| SCHEMBL30112251 | 0.75 | GABRA1 (0.51) | GABRA1GABRG2GABRB3DYRK1AGAA | |
| SCHEMBL23674502 | 0.75 | GABRA1 (0.51) | GABRA1GABRG2GABRB3DYRK1AIDO1 | |
| SCHEMBL155562 | 0.74 | GABRA1 (0.49) | GABRA1GABRG2GABRB3DYRK1AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4093509-A1 | SULFONIMIDAMIDE COMPOUNDS AS NLRP3 MODULATORS | F. Hoffmann-La Roche AG (CH) | 2022-11-30 | — | — | EP | disclosed |