Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 9/20 | 0.58 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.58 |
| ▸ | VCP | P55072 | 2/20 | 0.57 |
| ▸ | KIF11 | P52732 | 1/20 | 0.54 |
| ▸ | CSNK2A1 | P68400 | 3/20 | 0.53 |
| ▸ | MEN1 | O00255 | 3/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.52 |
| ▸ | GAA | P10253 | 1/20 | 0.52 |
| ▸ | RAB9A | P51151 | 1/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.50 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.50 |
| ▸ | CSNK2B | P67870 | 1/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.49 |
| ▸ | MPO | P05164 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23540008 | 1.00 | MAPT (0.58) | MAPTNPSR1VCPKIF11CSNK2A1 | |
| SCHEMBL23540004 | 0.86 | VCP (0.54) | MAPTNPSR1VCPKIF11CSNK2A1 | |
| SCHEMBL7268473 | 0.85 | MAPT (0.72) | MAPTNPSR1VCPKIF11CSNK2A1 | |
| SCHEMBL30041778 | 0.85 | CSNK2A1 (0.74) | MAPTNPSR1VCPCSNK2A1MEN1 | |
| SCHEMBL7268480 | 0.85 | CSNK2A1 (0.74) | MAPTNPSR1VCPCSNK2A1MEN1 | |
| SCHEMBL23539769 | 0.82 | MAPT (0.58) | MAPTNPSR1VCPKIF11CSNK2A1 | |
| SCHEMBL23539682 | 0.82 | VCP (0.62) | MAPTNPSR1VCPMEN1KMT2A | |
| SCHEMBL23554143 | 0.81 | VCP (0.61) | MAPTNPSR1VCPMEN1KMT2A | |
| SCHEMBL23554215 | 0.81 | VCP (0.61) | MAPTNPSR1VCPMEN1KMT2A | |
| SCHEMBL30041515 | 0.81 | VCP (0.61) | MAPTNPSR1VCPMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115279741-A | 4-phenyl-N- (phenyl) thiazol-2-amine derivatives and related compounds as Aryl Hydrocarbon Receptor (AHR) agonists for the treatment of, for example, angiogenesis-related disorders or inflammatory disorders | 医肯纳肿瘤学公司 | 2022-11-01 | — | — | CN | disclosed |