SCHEMBL30043354

SCHEMBL30043354

CN(C)Cc1ccc(-c2ccc(NC(=O)Nc3cccnc3Oc3ccccc3C(C)(C)C)c(F)c2)cc1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
P2RY1 P47900 20/20 1.00
KCNH2 Q12809 2/20 0.79
P2RY14 Q15391 1/20 0.55

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3154872 1.00 P2RY1 (1.00) P2RY1KCNH2P2RY14
SCHEMBL30042785 0.93 P2RY1 (1.00) P2RY1KCNH2P2RY14
SCHEMBL3151337 0.93 P2RY1 (1.00) P2RY1KCNH2P2RY14
SCHEMBL30042972 0.93 P2RY1 (1.00) P2RY1KCNH2P2RY14
SCHEMBL3146567 0.93 P2RY1 (1.00) P2RY1KCNH2P2RY14
SCHEMBL3154893 0.84 P2RY1 (1.00) P2RY1KCNH2P2RY14
SCHEMBL3150304 0.82 P2RY1 (1.00) P2RY1KCNH2P2RY14
SCHEMBL3159850 0.82 P2RY1 (0.85) P2RY1KCNH2P2RY14
SCHEMBL3155301 0.81 P2RY1 (0.84) P2RY1KCNH2P2RY14
SCHEMBL3163537 0.81 P2RY1 (1.00) P2RY1KCNH2P2RY14

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4094762-A1 TREATMENT OF NEUROLOGICAL INDICATIONS UCL Business Ltd (GB) 2022-11-30 EP disclosed