Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RY1 | P47900 | 20/20 | 1.00 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.79 |
| ▸ | P2RY14 | Q15391 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30043354 | 1.00 | P2RY1 (1.00) | P2RY1KCNH2P2RY14 | |
| SCHEMBL30042785 | 0.93 | P2RY1 (1.00) | P2RY1KCNH2P2RY14 | |
| SCHEMBL3151337 | 0.93 | P2RY1 (1.00) | P2RY1KCNH2P2RY14 | |
| SCHEMBL30042972 | 0.93 | P2RY1 (1.00) | P2RY1KCNH2P2RY14 | |
| SCHEMBL3146567 | 0.93 | P2RY1 (1.00) | P2RY1KCNH2P2RY14 | |
| SCHEMBL3154893 | 0.84 | P2RY1 (1.00) | P2RY1KCNH2P2RY14 | |
| SCHEMBL3150304 | 0.82 | P2RY1 (1.00) | P2RY1KCNH2P2RY14 | |
| SCHEMBL3159850 | 0.82 | P2RY1 (0.85) | P2RY1KCNH2P2RY14 | |
| SCHEMBL3155301 | 0.81 | P2RY1 (0.84) | P2RY1KCNH2P2RY14 | |
| SCHEMBL3163537 | 0.81 | P2RY1 (1.00) | P2RY1KCNH2P2RY14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1751113-B1 | UREA ANTAGONISTS OF P2Y1 RECEPTOR USEFUL IN THE TREATMENT OF THROMBOTIC CONDITIONS | BRISTOL MYERS SQUIBB CO (US) | 2010-03-10 | — | — | EP | claimed |
| US-7388021-B2 | Urea antagonists of P2Y1 receptor useful in the treatment of thrombotic conditions | BRISTOL MYERS SQUIBB COMPANY (US) | 2008-06-17 | — | — | US | claimed |
| US-20050267119-A1 | Urea antagonists of P2Y1 receptor useful in the treatment of thrombotic conditions | BRISTOL-MYERS SQUIBB COMPANY | 2005-12-01 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050267119-A1 | Urea antagonists of P2Y1 receptor useful in the treatment of thrombotic conditions | P2RY1, P2RY11, P2RY2 | P2RY1 1/4885KCNH2 2493/4885P2RY14 14/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.