Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 2/20 | 0.78 |
| ▸ | MAPK1 | P28482 | 6/20 | 0.40 |
| ▸ | AURKA | O14965 | 3/20 | 0.36 |
| ▸ | CDK2 | P24941 | 3/20 | 0.36 |
| ▸ | KCNQ3 | O43525 | 2/20 | 0.36 |
| ▸ | KCNQ2 | O43526 | 2/20 | 0.36 |
| ▸ | KCNQ4 | P56696 | 1/20 | 0.36 |
| ▸ | KCNQ5 | Q9NR82 | 1/20 | 0.36 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.36 |
| ▸ | MAPK3 | P27361 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL300356 | 1.00 | CNR2 (0.78) | CNR2MAPK1AURKACDK2KCNQ3 | |
| SCHEMBL300479 | 1.00 | CNR2 (0.78) | CNR2MAPK1AURKACDK2KCNQ3 | |
| SCHEMBL300487 | 1.00 | CNR2 (0.78) | CNR2MAPK1AURKACDK2KCNQ3 | |
| SCHEMBL300497 | 1.00 | CNR2 (0.78) | CNR2MAPK1AURKACDK2KCNQ3 | |
| SCHEMBL300533 | 1.00 | CNR2 (0.78) | CNR2MAPK1AURKACDK2KCNQ3 | |
| SCHEMBL300535 | 0.90 | CNR2 (0.65) | CNR2 | |
| SCHEMBL300486 | 0.90 | CNR2 (0.65) | CNR2 | |
| SCHEMBL13745625 | 0.88 | CNR2 (1.00) | CNR2MAPK1AURKACDK2KCNQ3 | |
| SCHEMBL176719 | 0.88 | CNR2 (1.00) | CNR2MAPK1AURKACDK2KCNQ3 | |
| SCHEMBL176651 | 0.88 | CNR2 (1.00) | CNR2MAPK1AURKACDK2KCNQ3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1937259-B1 | HEXAHYDRO-CYCLOHEPTAPYRAZOLE CANNABINOID MODULATORS | JANSSEN PHARMACEUTICA NV (BE) | 2011-11-23 | — | — | EP | claimed |