Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IL4I1 | Q96RQ9 | 7/20 | 0.58 |
| ▸ | TP53 | P04637 | 4/20 | 0.41 |
| ▸ | LMNA | P02545 | 3/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30948007 | 0.99 | IL4I1 (0.57) | IL4I1TP53LMNACYP1A2RXFP1 | |
| SCHEMBL30948107 | 0.98 | IL4I1 (0.58) | IL4I1TP53LMNACYP1A2RXFP1 | |
| SCHEMBL30948243 | 0.91 | IL4I1 (0.54) | IL4I1TP53LMNA | |
| SCHEMBL30948355 | 0.89 | IL4I1 (0.54) | IL4I1TP53LMNARXFP1 | |
| SCHEMBL30948046 | 0.88 | IL4I1 (0.58) | IL4I1TP53LMNARXFP1 | |
| SCHEMBL30948242 | 0.85 | IL4I1 (0.53) | IL4I1TP53LMNARXFP1 | |
| SCHEMBL30047175 | 0.82 | IL4I1 (0.60) | IL4I1TP53LMNARXFP1 | |
| SCHEMBL30947906 | 0.80 | TP53 (0.48) | IL4I1TP53LMNARXFP1 | |
| SCHEMBL30046889 | 0.79 | IL4I1 (0.77) | IL4I1TP53LMNARXFP1 | |
| SCHEMBL30045945 | 0.78 | IL4I1 (0.55) | IL4I1TP53LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4329889-A1 | IL4I1 INHIBITORS AND METHODS OF USE | Merck Sharp & Dohme LLC (US) | 2024-03-06 | — | — | EP | disclosed |
| WO-2022227015-A1 | IL4I1 INHIBITORS AND METHODS OF USE | MERCK SHARP & DOHME CORP. (US) | 2022-11-03 | — | — | WO | disclosed |
| WO-2022232333-A1 | IL4I1 INHIBITORS AND METHODS OF USE | MERCK SHARP & DOHME LLC (US) | 2022-11-03 | — | — | WO | disclosed |