Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | PKM | P14618 | 1/20 | 0.32 |
| ▸ | CNR1 | P21554 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | BCL6 | P41182 | 1/20 | 0.30 |
| ▸ | MELK | Q14680 | 1/20 | 0.30 |
| ▸ | BCHE | P06276 | 1/20 | 0.30 |
| ▸ | ACHE | P22303 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23856679 | 1.00 | ALDH1A1 (0.34) | ALDH1A1SMN1; SMN2PKMCNR1KMT2A | |
| SCHEMBL23857721 | 0.79 | — | — | |
| SCHEMBL23856660 | 0.78 | ACACB (0.33) | — | |
| SCHEMBL23856825 | 0.78 | CHEK1 (0.30) | SMN1; SMN2 | |
| SCHEMBL30047126 | 0.78 | CHEK1 (0.30) | SMN1; SMN2 | |
| SCHEMBL30046636 | 0.77 | STK17B (0.38) | CNR1 | |
| SCHEMBL23871671 | 0.77 | STK17B (0.38) | CNR1 | |
| SCHEMBL23857342 | 0.76 | — | — | |
| SCHEMBL23871601 | 0.75 | SYK (0.35) | KMT2A | |
| SCHEMBL30047172 | 0.75 | SYK (0.35) | KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115298176-A | Compounds and their use in the treatment of bacterial infections | 豪夫迈·罗氏有限公司 | 2022-11-04 | — | — | CN | disclosed |