Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 1/20 | 0.44 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.34 |
| ▸ | FFAR2 | O15552 | 1/20 | 0.33 |
| ▸ | PPARG | P37231 | 3/20 | 0.33 |
| ▸ | PPARA | Q07869 | 3/20 | 0.33 |
| ▸ | EGFR | P00533 | 1/20 | 0.33 |
| ▸ | GPR6 | P46095 | 3/20 | 0.32 |
| ▸ | MME | P08473 | 1/20 | 0.32 |
| ▸ | ACKR3 | P25106 | 2/20 | 0.32 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.32 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.32 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.31 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL176604 | 0.90 | CNR2 (0.50) | CNR2CHRM4FFAR2EGFRGPR6 | |
| SCHEMBL176637 | 0.85 | CNR2 (0.47) | CNR2CHRM4FFAR2GPR6MME | |
| SCHEMBL176445 | 0.83 | CNR2 (0.59) | CNR2CHRM4ACKR3TRPV1 | |
| SCHEMBL3470458 | 0.82 | CNR2 (0.42) | CNR2CHRM4PPARGPPARACHRM2 | |
| SCHEMBL176486 | 0.80 | CNR2 (0.49) | CNR2CHRM4TRPV1 | |
| SCHEMBL176525 | 0.80 | CNR2 (0.52) | CNR2CHRM4PPARGGPR6ACKR3 | |
| SCHEMBL176749 | 0.80 | CNR2 (0.52) | CNR2CHRM4PPARGGPR6ACKR3 | |
| SCHEMBL300486 | 0.75 | CNR2 (0.65) | CNR2FFAR2EGFRMME | |
| SCHEMBL300535 | 0.75 | CNR2 (0.65) | CNR2FFAR2EGFRMME | |
| SCHEMBL176498 | 0.72 | CNR2 (0.56) | CNR2EGFR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1937259-B1 | HEXAHYDRO-CYCLOHEPTAPYRAZOLE CANNABINOID MODULATORS | JANSSEN PHARMACEUTICA NV (BE) | 2011-11-23 | — | — | EP | claimed |