Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPD | P32754 | 2/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.48 |
| ▸ | BRD4 | O60885 | 2/20 | 0.48 |
| ▸ | BRPF1 | P55201 | 2/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | GLA | P06280 | 1/20 | 0.44 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.43 |
| ▸ | CASP3 | P42574 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | ATM | Q13315 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24815337 | 1.00 | HPD (0.52) | HPDSMN1; SMN2KDM4EALDH1A1BRD4 | |
| SCHEMBL7539164 | 0.85 | SMN1; SMN2 (0.65) | SMN1; SMN2KDM4EALDH1A1BRD4BRPF1 | |
| SCHEMBL24815336 | 0.84 | SLC22A12 (0.57) | HPDSMN1; SMN2KDM4EALDH1A1BRD4 | |
| SCHEMBL24812336 | 0.84 | HPD (0.55) | HPDSMN1; SMN2KDM4EALDH1A1BRD4 | |
| SCHEMBL30049030 | 0.84 | SLC22A12 (0.57) | HPDSMN1; SMN2KDM4EALDH1A1BRD4 | |
| SCHEMBL25139613 | 0.82 | HPD (0.54) | HPDSMN1; SMN2KDM4EALDH1A1BRD4 | |
| SCHEMBL6054648 | 0.82 | HPD (0.46) | HPDSMN1; SMN2KDM4EALDH1A1BRD4 | |
| SCHEMBL6054650 | 0.81 | HPD (0.48) | HPDSMN1; SMN2KDM4EALDH1A1BRD4 | |
| SCHEMBL25139664 | 0.80 | HPD (0.52) | HPDSMN1; SMN2KDM4EALDH1A1BRD4 | |
| SCHEMBL27446319 | 0.78 | HPD (0.62) | HPDSMN1; SMN2KDM4EALDH1A1BRD4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4358954-A1 | CDK2 INHIBITORS AND METHODS OF USING THE SAME | Cedilla Therapeutics, Inc. (US) | 2024-05-01 | — | — | EP | disclosed |
| WO-2022272106-A1 | CDK2 INHIBITORS AND METHODS OF USING THE SAME | CEDILLA THERAPEUTICS, INC. (US) | 2022-12-29 | — | — | WO | disclosed |