SCHEMBL30048909

SCHEMBL30048909

[Sn].c1cnc2ccsc2c1

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 6/20 0.46
HSD17B10 Q99714 2/20 0.46
LMNA P02545 3/20 0.44
KDM4E B2RXH2 3/20 0.41
MAPT P10636 3/20 0.41
ABCB1 P08183 1/20 0.37
NPC1 O15118 2/20 0.34
RAB9A P51151 2/20 0.34
POLB P06746 1/20 0.34
PDPK1 O15530 1/20 0.34
PDK1 Q15118 1/20 0.34
CYP2A6 P11509 1/20 0.34
HTT P42858 3/20 0.33
METAP1 P53582 1/20 0.33
HPGD P15428 1/20 0.33
PPARG P37231 1/20 0.33
NCOA2 Q15596 1/20 0.33
NCOA1 Q15788 1/20 0.33
TDP1 Q9NUW8 1/20 0.33
NCOA3 Q9Y6Q9 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29368123 0.98
SCHEMBL23806 0.98
SCHEMBL29894511 0.95 ALDH1A1 (0.46) ALDH1A1HSD17B10LMNAKDM4EMAPT
SCHEMBL28027613 0.95 ALDH1A1 (0.46) ALDH1A1HSD17B10LMNAKDM4EMAPT
Hydrochloric Acid SCHEMBL6309590 0.95 ALDH1A1 (0.46) ALDH1A1HSD17B10LMNAKDM4EMAPT
Ethane SCHEMBL28746668 0.93 ALDH1A1 (0.45) ALDH1A1HSD17B10LMNAKDM4EMAPT
Thiophene SCHEMBL27637023 0.90 ALDH1A1 (0.42) ALDH1A1HSD17B10LMNAKDM4EMAPT
SCHEMBL21803454 0.90 ALDH1A1 (0.42) ALDH1A1HSD17B10LMNAKDM4EMAPT
Phosphoric Acid SCHEMBL28904005 0.86 ALDH1A1 (0.39) ALDH1A1HSD17B10LMNAKDM4EMAPT
Formic Acid SCHEMBL29999237 0.86 ALDH1A1 (0.39) ALDH1A1HSD17B10LMNAKDM4EMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4330382-A2 IN VITRO DRUGS FROM PRODRUGS AND USE THEREOF Brandenburgische Technische Universität Cottbus-Senftenberg (DE) 2024-03-06 EP disclosed
WO-2022229050-A2 IN VITRO DRUGS FROM PRODRUGS AND USE THEREOF BRANDENBURGISCHE TECHNISCHE UNIVERSITÄT COTTBUS-SENFTENBERG (DE) 2022-11-03 WO disclosed