SCHEMBL30048971 — predicted protein targets

Predicted protein targets (top 15)

	gene	UniProt	supporting neighbours	confidence
▸	AAK1	Q2M2I8	13/20	0.55

▸	MAPT	P10636	4/20	0.43

▸	ALDH1A1	P00352	2/20	0.43

▸	CTSS	P25774	2/20	0.41

▸	CTSK	P43235	2/20	0.41

▸	KDM4E	B2RXH2	1/20	0.40

▸	CYP1A2	P05177	1/20	0.40

▸	CYP3A4	P08684	1/20	0.40

▸	CYP2D6	P10635	1/20	0.40

▸	CYP2C9	P11712	1/20	0.40

▸	CYP2C19	P33261	1/20	0.40

▸	CTSB	P07858	1/20	0.40

▸	SMN1; SMN2	Q16637	1/20	0.40

▸	POLB	P06746	1/20	0.40

▸	ATM	Q13315	1/20	0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
SCHEMBL30048937	0.80	AAK1 (0.54)	AAK1MAPTALDH1A1SMN1; SMN2POLB
SCHEMBL24638289	0.80	AAK1 (0.54)	AAK1MAPTALDH1A1SMN1; SMN2POLB
SCHEMBL24638293	0.79	AAK1 (0.50)	AAK1MAPTSMN1; SMN2POLBATM
SCHEMBL4975833	0.78	AAK1 (0.52)	AAK1MAPTALDH1A1CYP1A2CYP3A4
SCHEMBL31167627	0.78	AAK1 (0.52)	AAK1MAPTALDH1A1CYP1A2CYP3A4
SCHEMBL23336740	0.76	AAK1 (0.56)	AAK1MAPTALDH1A1CTSSCTSK
SCHEMBL22664910	0.76	AAK1 (0.56)	AAK1MAPTALDH1A1CTSSCTSK
SCHEMBL29418317	0.76	AAK1 (0.56)	AAK1MAPTALDH1A1CTSSCTSK
SCHEMBL24638300	0.76	AAK1 (0.54)	AAK1
SCHEMBL30050178	0.76	AAK1 (0.54)	AAK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
WO-2022231242-A1	INDAZOLE COMPOUND HAVING LRRK2 INHIBITORY ACTIVITY	주식회사 스탠다임	2022-11-03	—	—	WO	disclosed