Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AAK1 | Q2M2I8 | 4/20 | 0.50 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.44 |
| ▸ | WDR77 | Q9BQA1 | 1/20 | 0.44 |
| ▸ | HIF1A | Q16665 | 5/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | ATM | Q13315 | 1/20 | 0.37 |
| ▸ | BACE1 | P56817 | 1/20 | 0.36 |
| ▸ | BACE2 | Q9Y5Z0 | 1/20 | 0.36 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.36 |
| ▸ | USP30 | Q70CQ3 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | CA1 | P00915 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
| ▸ | CA9 | Q16790 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL65546 | 0.81 | AAK1 (0.53) | AAK1PRMT5WDR77HIF1APOLB | |
| SCHEMBL22664660 | 0.80 | AAK1 (0.52) | AAK1PRMT5WDR77HIF1APOLB | |
| SCHEMBL16813062 | 0.80 | AAK1 (0.52) | AAK1PRMT5WDR77HIF1APOLB | |
| SCHEMBL29418593 | 0.80 | AAK1 (0.52) | AAK1PRMT5WDR77HIF1APOLB | |
| SCHEMBL30048971 | 0.79 | AAK1 (0.55) | AAK1POLBATMMAPTSMN1; SMN2 | |
| SCHEMBL2428565 | 0.77 | LPL (0.39) | AAK1HIF1ACA1CA2CA9 | |
| SCHEMBL2592447 | 0.77 | AAK1 (0.55) | AAK1PRMT5WDR77ATMDGAT1 | |
| SCHEMBL19980304 | 0.77 | AAK1 (0.45) | AAK1PRMT5WDR77HIF1ABACE1 | |
| SCHEMBL16491250 | 0.75 | AAK1 (0.64) | AAK1PRMT5WDR77HIF1ADGAT1 | |
| SCHEMBL16491251 | 0.75 | AAK1 (0.64) | AAK1PRMT5WDR77HIF1ADGAT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022231242-A1 | INDAZOLE COMPOUND HAVING LRRK2 INHIBITORY ACTIVITY | 주식회사 스탠다임 | 2022-11-03 | — | — | WO | disclosed |