Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.52 |
| ▸ | CYP3A4 | P08684 | 11/20 | 0.52 |
| ▸ | CYP2D6 | P10635 | 11/20 | 0.52 |
| ▸ | CYP2C9 | P11712 | 8/20 | 0.52 |
| ▸ | TSHR | P16473 | 7/20 | 0.52 |
| ▸ | CYP1A2 | P05177 | 6/20 | 0.52 |
| ▸ | CYP2C19 | P33261 | 6/20 | 0.52 |
| ▸ | USP2 | O75604 | 4/20 | 0.52 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | TP53 | P04637 | 1/20 | 0.48 |
| ▸ | GAA | P10253 | 3/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27162872 | 1.00 | ALDH1A1 (0.53) | ALDH1A1SMN1; SMN2CYP3A4CYP2D6CYP2C9 | |
| SCHEMBL27161993 | 0.92 | CYP3A4 (0.58) | ALDH1A1SMN1; SMN2CYP3A4CYP2D6CYP2C9 | |
| SCHEMBL30050081 | 0.92 | CYP3A4 (0.58) | ALDH1A1SMN1; SMN2CYP3A4CYP2D6CYP2C9 | |
| SCHEMBL31097543 | 0.87 | ALDH1A1 (0.57) | ALDH1A1SMN1; SMN2CYP3A4CYP2D6CYP2C9 | |
| SCHEMBL27162633 | 0.87 | ALDH1A1 (0.57) | ALDH1A1SMN1; SMN2CYP3A4CYP2D6CYP2C9 | |
| SCHEMBL30050943 | 0.82 | SMN1; SMN2 (0.49) | ALDH1A1SMN1; SMN2CYP3A4CYP2D6CYP2C9 | |
| SCHEMBL27162174 | 0.82 | SMN1; SMN2 (0.49) | ALDH1A1SMN1; SMN2CYP3A4CYP2D6CYP2C9 | |
| SCHEMBL30049877 | 0.82 | ALDH1A1 (0.53) | ALDH1A1SMN1; SMN2CYP3A4CYP2D6CYP2C9 | |
| SCHEMBL27162435 | 0.82 | ALDH1A1 (0.53) | ALDH1A1SMN1; SMN2CYP3A4CYP2D6CYP2C9 | |
| SCHEMBL30050728 | 0.81 | ALDH1A1 (0.60) | ALDH1A1SMN1; SMN2CYP3A4CYP2D6CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4330248-A1 | PYRIDINE-SULFONAMIDE DERIVATIVES AS SIGMA LIGANDS | Acondicionamiento Tarrasense (ES) | 2024-03-06 | — | — | EP | claimed |
| WO-2022229405-A1 | PYRIDINE-SULFONAMIDE DERIVATIVES AS SIGMA LIGANDS | ACONDICIONAMIENTO TARRASENSE (ES) | 2022-11-03 | — | — | WO | claimed |
| EP-4330248-A1 | PYRIDINE-SULFONAMIDE DERIVATIVES AS SIGMA LIGANDS | Acondicionamiento Tarrasense (ES) | 2024-03-06 | — | — | EP | disclosed |
| WO-2022229405-A1 | PYRIDINE-SULFONAMIDE DERIVATIVES AS SIGMA LIGANDS | ACONDICIONAMIENTO TARRASENSE (ES) | 2022-11-03 | — | — | WO | disclosed |