SCHEMBL30050872

SCHEMBL30050872

CCCCCCC(CC)c1ncccc1N

nearest known ligand 0.39

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
ADA P00813 3/20 0.39
NR1I2 O75469 1/20 0.38
TLR8 Q9NR97 2/20 0.38
CYP1A2 P05177 1/20 0.36
CYP2C9 P11712 1/20 0.36
CYP2C19 P33261 1/20 0.36
FAAH O00519 8/20 0.35
DAGLA Q9Y4D2 5/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15640158 1.00 ADA (0.39) ADANR1I2TLR8CYP1A2CYP2C9
SCHEMBL30020799 1.00 ADA (0.39) ADANR1I2TLR8CYP1A2CYP2C9
SCHEMBL19779926 0.84 TLR8 (0.38) ADATLR8CYP1A2CYP2C9CYP2C19
SCHEMBL29814520 0.79 ADA (0.39) ADANR1I2TLR8FAAHDAGLA
SCHEMBL29882503 0.77 HPGD (0.43) NR1I2CYP1A2CYP2C9CYP2C19
SCHEMBL26041690 0.76 FAAH (0.37) NR1I2TLR8FAAHDAGLA
SCHEMBL21888617 0.76 FAAH (0.37) NR1I2TLR8FAAHDAGLA
Hydrochloric Acid SCHEMBL29882270 0.75 HPGD (0.42) NR1I2CYP1A2CYP2C9CYP2C19
SCHEMBL26546032 0.75 NR1I2 (0.41) NR1I2FAAHDAGLA
SCHEMBL23870976 0.75 FAAH (0.36) NR1I2FAAHDAGLA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-110225912-B GSK-3 inhibitors 百时美施贵宝公司 2022-10-21 CN disclosed